市场调查报告书
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1447738
疫苗佐剂市场评估:按产品类型、给药途径、疾病类型、应用和地区划分的机会和预测(2017-2031)Vaccine Adjuvants Market Assessment, By Product Type, By Route of Administration, Disease Type, By Application, By Region, Opportunities and Forecast, 2017-2031F |
全球疫苗佐剂市场规模预计将从2023年的13.3亿美元成长到2031年的28.4亿美元,2024-2031年预测期内复合年增长率为9.95%,预计规模也将持续扩大。
由于几个关键因素,全球疫苗佐剂市场正在经历显着成长。 传染病的爆发导致疫苗需求增加,支持市场扩张。 生物技术的技术进步也在推动市场发展方面发挥着重要作用。 此外,政府对研发活动的资助和投资的增加也推动了这一成长轨迹。 主要参与者之间的策略联盟和合作也是促进市场拓展的重要因素。
对疫苗、生物製药和治疗药物的需求不断增加
比以往任何时候都需要更多的疫苗、生物製药和治疗方法。 COVID-19 让疫苗在现在和未来变得更加重要。 疫苗佐剂是疫苗的重要组成部分,随着疫苗使用量的增加,对疫苗佐剂的需求也会增加。 在医疗领域,生物製药、基因治疗药物、细胞治疗药物越来越受欢迎。 人口成长、疾病传播、大流行威胁、新冠疫情后的应对措施以及公众意识的提高等因素将推动未来几年对疫苗佐剂的需求。
传染病疫情蔓延
由于气候变迁、快速都市化和土地利用模式变化等多种因素,传染病的流行正在增加。 这些因素导致新疾病的出现、旧疾病的重新出现以及现有疾病的传播。 技术变革,例如医疗保健的改善和全球旅行,也会导致传染病的传播。 此外,人口成长和移民等人口变化也会增加疾病爆发的风险。 随着传染病流行的增加,对疫苗的需求也增加。 世界卫生组织(WHO)估计,全球每年约三分之一的死亡是由传染病造成的,其中急性呼吸道感染、胃肠道感染、结核病和疟疾是全球主要疾病,造成大部分死亡。
碳水化合物佐剂成长迅速
以碳水化合物为基础的佐剂在疫苗开发中越来越受欢迎。 它们被认为是安全的并且与身体相容,并且可以诱导和控制免疫反应。 这些佐剂与次单位疫苗搭配使用,可以帮助增强人体的免疫反应,使疫苗更有效。 天然和合成碳水化合物已在临床试验中作为佐剂进行了测试,其中一些已被批准用于人类疫苗。 碳水化合物佐剂具有多种优点,包括与身体更好的相容性、更好的耐受性和更高的安全性。 从这些角度来看,它被认为是一种有前途的疫苗佐剂。
本报告调查了全球疫苗佐剂市场,提供了市场定义和概述、市场规模趋势和预测、各个细分市场和地区的详细分析、行业结构以及影响市场成长的因素分析、案例研究、竞争格局、主要公司的简介等等。
Global vaccine adjuvants market is projected to witness a CAGR of 9.95% during the forecast period 2024-2031F, growing from USD 1.33 billion in 2023 to USD 2.84 billion in 2031. The global vaccine adjuvants market is witnessing substantial growth driven by several key factors. The increasing prevalence of infectious diseases has led to a rising demand for vaccines, propelling market expansion. Technological advancements in biotechnology are also playing a significant role in driving the market forward. Moreover, increased government funding and investments in research and development activities are fueling this growth trajectory. Strategic collaborations and partnerships among key industry players are also acting as crucial factors contributing to the market's expansion. Vaccine adjuvants enhance immunogenicity, leading to more effective vaccines with reduced antigen content, crucial for mass vaccination campaigns. However, challenges like side effects and toxicity associated with some adjuvants, particularly aluminum adjuvants, which can cause local injection site reactions and allergic responses hinder the market. Additionally, the concern for public health and safety may limit the adoption of certain adjuvants if they pose risks or potential harm to individuals receiving them.
In October 2023, after careful evaluation, the World Health Organization (WHO) approved the use of the R21/Matrix-M malaria vaccine. Developed by the University of Oxford, the Serum Institute of India, and leveraging Novavax's adjuvant technology, the vaccine has met strict standards for safety, quality, and effectiveness. Experts from the WHO's independent advisory groups, SAGE and MPAG, conducted a thorough review and found that the vaccine is effective and safe. Clinical trials in various regions with different malaria transmission rates have demonstrated its efficacy.
Growing Demand for Vaccines, Biopharmaceuticals, and Therapy Products
More vaccines, biopharmaceuticals, and therapies are needed than ever before. COVID-19 has made vaccines even more essential, both now and in the future. Vaccine adjuvants are essential components of vaccines and increasing the use of vaccines will ultimately enhance the demand for vaccine adjuvants. In the medical sector, biopharmaceuticals, gene therapies, and cell therapies are becoming more and more popular. Factors, such as population growth, escalating disease prevalence, pandemic threats, post-COVID readiness measures, and heightened public awareness, are driving the demand for vaccine adjuvants in the upcoming years.
As per the WHO report published in May 2023, between the years 2019 and 2021, a significant increase in the consumption of vaccines has been observed. The adult vaccines segment grew by 15%, pediatric vaccines registered a growth of 8%, and vaccines used for adolescents registered a growth of 7%. This data does not consider COVID-19 vaccines, but still, a significant change in demand can be seen.
Growing Prevalence of Infectious Diseases
The prevalence of infectious diseases is increasing due to several factors, including climate change, rapid urbanization, and changes in land-use patterns. These factors contribute to the emergence of new diseases, the re-emergence of old diseases, and the spread of existing diseases. Technological changes, such as improved health care and global travel, also contribute to the spread of infectious diseases. Additionally, demographic changes, such as population growth and migration, can increase the risk of disease emergence. As the prevalence of infectious diseases increases, the demand for vaccines rises, subsequently enhancing the market demand for vaccine adjuvants as they are essential components of the finished vaccines. The World Health Organization estimates that approximately one-third of annual deaths worldwide are attributed to infectious diseases, with acute respiratory tract infections, gastrointestinal infections, tuberculosis, and malaria causing most of the illnesses and mortality worldwide.
For instance, as per the data published by Worldometers, over 703 million COVID-19 cases were reported till February 2024, along with 69 million deaths reported. COVID-19 has been the most contagious and lethal infectious disease in recent times.
Carbohydrate-based Adjuvants are Fastest Growing
Carbohydrate-based adjuvants are becoming increasingly popular in vaccine development. They are considered safe and compatible with the body, and they can trigger and control immune responses. These adjuvants help make vaccines more effective by boosting the body's immune response when used with subunit vaccines. Natural and synthetic carbohydrates have been tested as adjuvants in clinical trials, and some have been approved for use in human vaccines. Carbohydrate-based adjuvants offer several advantages, including being highly compatible with the body, well-tolerated, and having a good safety record. These factors make them promising candidates for use as adjuvants in vaccines.
Infectious Disease to be the Leading Disease Type
The infectious disease segment is expected to be the leading disease type for utilizing vaccines for treatment purposes. A variety of vaccines are available in the market for infectious diseases like hepatitis, polio, tetanus, and influenza. Vaccines are highly effective in infectious diseases because they provide long-lasting immunity, protect against severe illness and death, and reduce the spread of the disease within a population. Vaccines work by imitating an infection, engaging the body's natural immune response, and providing protection without the dangers of a full-blown infection. Vaccines are more effective in infectious diseases because they target specific pathogens, and their development is based on the characteristics of the pathogen, such as antigenic stability, serotype, and the presence of diagnostic tests or clinical criteria for measuring disease burden.
In May 2023, GSK announced the US Food and Drug Administration's approval for its Arexvy (respiratory syncytial virus vaccine, adjuvanted) meant for the prevention of lower respiratory tract disease (LRTD) caused due to respiratory syncytial virus (RSV) in patients of 60 years of age and older. Arexvy is the world's first RSV vaccine for elders to be approved.
North America to be the Dominating Region
North America's leadership in the vaccine adjuvant market stems from several key reasons. Governments are investing heavily in research, and companies within the industry are partnering to achieve breakthroughs. The region's healthcare system is well-developed, with a focus on preventive care. This encourages the use of adjuvanted vaccines, which make vaccines more effective and are thoroughly tested before being approved. This reflects the region's commitment to preventive healthcare measures. Additionally, the region's strong regulatory framework ensures the safety and efficacy of adjuvanted vaccines, further boosting market confidence. US FDA considers vaccine adjuvant as a part of the vaccine and not as a separate entity, thus separate approval for vaccine adjuvant is not required.
Future Market Scenario
The future of vaccine adjuvants is expected to focus on the development of new, more effective, and safer adjuvants. Research is being conducted to create adjuvants that can enhance the immune response to vaccines, particularly for subunit vaccines, which are often less effective at generating a robust immune response. New adjuvants are being developed from natural resources and synthetic components, to improve safety and protective efficacy. Technologies, such as nanotechnologies and molecular biology, are being used to improve vaccine efficacy, and adjuvants are being designed to stimulate immune responses in a more targeted manner. Additionally, systems vaccinology approaches are being used to assess and characterize new adjuvant systems, which may help in the rational design of vaccines in the future.
Key Players Landscape and Outlook
Brenntag Biosector A/S, OZ Biosciences, Agenus, Inc., Spectrum Pharmaceuticals, Inc., SEPPIC, Inc., Novavax, Inc., and MPV Technologies are some of the key players in the vaccine adjuvants market. These companies are actively involved in the production and advancement of vaccine adjuvants, contributing to the growth and innovation within the industry. The market is competitive, with a focus on enhancing vaccine efficacy, reducing production costs, and developing safer and more effective vaccines through ongoing advancements in technology and formulations.
In February 2024, DTRA's JSTO awarded a USD 31 million, 5-year contract to Ginkgo Bioworks and SaponiQx through the MCDC program to develop cutting-edge vaccine adjuvants. Ginkgo, specializing in cell programming and biosecurity, and SaponiQx, with its innovative adjuvant platform, have been collaborating on this project since 2021.
All segments will be provided for all regions and countries covered
Companies mentioned above DO NOT hold any order as per market share and can be changed as per information available during research work.