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市场调查报告书
商品编码
1856133
全球胜肽合成市场-市场份额和排名、总收入和需求预测(2025-2031 年)Peptide Synthesis - Global Market Share and Ranking, Overall Sales and Demand Forecast 2025-2031 |
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2024 年全球胜肽合成市场规模估计为 6.99 亿美元,预计到 2031 年将达到 10.94 亿美元,在 2025-2031 年预测期内复合年增长率为 6.7%。
胜肽合成是指利用化学或生物化学方法将特定序列的多个胺基酸连接成胜肽链的过程。这些胜肽可用作治疗药物、诊断剂、生物标记和研究工具。胜肽通常比蛋白质短,通常由不超过40-60个胺基酸残基组成,但其结构可能很复杂,可能包含非天然或修饰的胺基酸、环化、与化学基团偶联以及标记。主要的胜肽合成技术包括固相胜肽合成(SPPS)、液相胜肽合成(LPPS)、混合/汇聚合成法、酵素法和重组表现。合成流程通常包括胺基酸的保护和去保护、胜肽键形成(偶联)、载体/树脂锚定、纯化(层析法步骤、沉淀等)以及严格的品管(结构确认、立体化学纯度、杂质/残留溶剂分析)。肽类药物、诊断和化妆品应用的快速发展,以及对高特异性、低毒性和强生物相容性的需求不断增长,使得肽合成成为生物製药和生命科学研究与开发的关键组成部分。
目前,肽合成市场正处于曲折点。一方面,基于胜肽的疗法在慢性病、代谢性疾病、肿瘤和神经退化等领域日益普及。其高特异性、低全身毒性和新型标靶机制使其在传统小分子和大蛋白药物难以发挥作用的领域展现出巨大潜力。另一方面,许多国家(例如美国、欧盟、日本和中国)的政府和监管机构已推出政策,支持创新,简化新型胜肽和胜肽-寡核苷酸(TIDES)药物的核准途径,并缩短临床试验和监管审查时间,从而扩大了胜肽合成供应商的市场机会。在技术方面,固相合成(SPPS)、液相合成(LPPS)、混合/汇聚合成方法的不断进步,以及复杂结构(包括非天然氨基酸、环化和胜肽-药物偶联物)合成能力的提升,正推动市场朝着更大规模、更高品质和更多样化的结构发展。此外,下游CDMO/CRO外包需求正在迅速成长。药物研发企业越来越倾向于将製程开发、规模化生产以及临床/註册生产外包给专业的合成/生产营业单位,以降低资本负担和风险。新兴经济体(例如中国、印度和韩国)也是这一趋势的强劲驱动力,这得益于不断增长的医疗需求、对生物技术的投资、不断下降的生产成本以及有利的政策激励措施。
然而,肽合成市场并非没有重大挑战和风险。首先,合成长肽或复杂胜肽(例如,带有修饰、非天然残基、环化或疏水序列的胜肽)时,偶联效率低、反应不完全、外消旋化和副产物生成等问题会被放大,导致产率降低,纯化成本高且难度高。其次,上游原料(高纯度保护胺基酸、专用耦合试剂、保护基以及稀有或合成修饰胺基酸)的供应链稳定性和成本差异很大。第三,下游纯化和品管步骤(层析法、去除残留试剂、保护基和溶剂、结构确认和立体化学纯度测定)需要大量的资本投入、较长的週期和较高的营运成本,尤其是在临床和商业规模上。各国对胜肽和生技药品(或其他类别)的定义、监管标准以及环境和化学安全政策的差异,会增加合规成本并导致延误。最后,竞争压力和价格战正在加剧,尤其是在 CDMO/合成服务供应商和以成本为导向的新兴市场。
下游需求正朝着多个方向同步发展。治疗性胜肽仍然是最大的驱动力。越来越多的胜肽类药物获得监管部门核准,研发开发平臺也不断扩展,尤其是在代谢性疾病(如肥胖症、糖尿病)、肿瘤、内分泌调节和感染疾病等领域。肽-药物偶联物和胜肽疫苗已成为多个疾病领域的关键研究方向。除了治疗性应用外,诊断和成像标记肽,例如生物标记、体外诊断试剂(IVD)以及放射性标记或萤光标记的小肽,需求也在不断增长,尤其是在精准医疗领域。在化妆品/美容行业,具有抗衰老、修復、促进胶原蛋白生成和抗氧化等功能的胜肽正被积极引入市场,从而推动了消费者和品牌对天然、生物活性和安全成分的更高期望。在自动化和高通量合成工具的推动下,研究和基础科学需求保持稳定,这促使学术机构和生物技术新兴企业寻求更灵活、更快速的客製化胜肽合成服务。总体而言,下游需求正朝着更复杂的结构、更先进的改进、更高的纯度和更客製化的应用方向发展,这要求更快的周转时间和更高的服务品质。
本报告旨在全面概述全球胜肽合成市场,重点关注总销售收入、市场份额和主要企业的排名,并按地区/国家、类型和应用进行分析。
胜肽合成市场规模、估算和预测报告提供了2020年至2031年期间的历史数据和预测数据,以销售收入(百万美元)为单位,2024年为基准年。定量和定性分析有助于读者制定业务/成长策略、评估市场竞争格局、分析公司在当前市场中的地位,并在胜肽合成领域做出明智的商业决策。
The global market for Peptide Synthesis was estimated to be worth US$ 699 million in 2024 and is forecast to a readjusted size of US$ 1094 million by 2031 with a CAGR of 6.7% during the forecast period 2025-2031.
Peptide synthesis refers to the process of linking multiple amino acids into a peptide chain in a specified sequence by chemical or biochemical methods. These peptides may serve as therapeutics, diagnostic reagents, biomarkers, or research tools. Peptides are generally shorter than proteins - most often composed of no more than 40-60 amino acid residues - though their structures can be complex, including non-natural or modified amino acids, cyclizations, conjugations with chemical moieties or labels. The main techniques for peptide synthesis include solid-phase peptide synthesis (SPPS), liquid-phase peptide synthesis (LPPS), hybrid/convergent methods, enzymatic or recombinant expression methods. The synthetic workflow typically involves protecting and deprotecting amino acids, peptide bond formation (coupling), support/resin anchoring or carrier systems, purification (such as chromatographic steps, precipitations, etc.), and rigorous quality control (structure confirmation, stereochemical purity, impurity/residual solvent analysis). With the rapid expansion of peptide-based drugs, diagnostics, and cosmetic applications, combined with growing demand for high specificity, low toxicity, and strong biocompatibility, peptide synthesis has become a cornerstone in biopharma and life science R&D.
The peptide synthesis market currently stands at a multi-accelerated inflection point. On one side, peptide-based therapeutics are being increasingly recognized in fields such as chronic diseases, metabolic disorders, oncology, and neurodegeneration: their high specificity, low systemic toxicity, and novel targeting mechanisms make them promising where traditional small molecules or large proteins struggle. On another side, governments and regulatory agencies in many countries (including the U.S., EU, Japan, China, etc.) are introducing policies that support innovation, streamline approval pathways for novel peptides or peptide/oligonucleotide (TIDES) drugs, and shorten clinical trial and regulatory review timelines, thereby enlarging market opportunity for peptide synthesis providers. On the technical front, continued progress in solid-phase synthesis (SPPS), liquid-phase methods (LPPS), hybrid / convergent synthesis, and enhanced capabilities for complex structures (including non-natural amino acids, cyclization, peptide-drug conjugates) are pushing the market toward larger scale, higher quality, and greater structural diversity. In addition, downstream CDMO/CRO outsourcing demand is rising sharply: drug developers are increasingly preferring to externalize process development, scale-up, and clinical/registration production to specialized synthesis/manufacturing entities to reduce capital burden and risk. Emerging economies (e.g. China, India, South Korea) are also providing strong growth drivers due to their rising healthcare needs, biotech investment, lower manufacturing cost bases, and favorable policy incentives.
However, the peptide synthesis market is not without substantial challenges and risks. First, synthesizing long or complex peptides (with modifications, non-natural residues, cyclization, hydrophobic sequences etc.) amplifies problems of low coupling efficiency, incomplete reactions, racemization, side-product formation - these reduce yield and make purification expensive and difficult. Second, the supply chain stability and cost volatility for upstream raw materials (high-purity protected amino acids, specialized coupling reagents, protective groups, rare or synthetic modified amino acids) is high; environmental / safety laws regulating chemical reagents and solvents impose increasing constraints. Third, downstream purification and quality control steps (chromatography, removal of residual reagents/protection groups/solvents, structure confirmation, stereochemical purity) require heavy equipment investment, long cycles, and high operating costs, particularly at clinical/commercial scale. Regulatory risk is also real: differing national definitions of peptides vs biologics (or other categories), regulatory standards, and environmental / chemical safety policies may shift, increasing compliance cost or causing delays. Finally, competitive pressures and pricing squeeze are intensifying, especially among CDMOs / synthesis service providers, and in emerging markets focusing on low cost; maintaining high quality, speed, and regulatory compliance becomes a differentiator but also a cost center.
Downstream demand is evolving in several concurrent directions. Therapeutic peptides continue to be the largest pull: more peptide drugs are gaining regulatory approval, and the R&D pipeline is expanding, especially in metabolic disease (e.g. obesity, diabetes), oncology, endocrine regulation, and infectious diseases. In several disease areas, peptide-drug conjugates and peptide vaccines are emerging as key focus areas. Beyond therapeutics, diagnostic and imaging labelled peptides are growing demand, e.g. biomarkers, in vitro diagnostics (IVD) and radiolabelled or fluorescent labelled small peptides, especially in precision medicine. The cosmetics / beauty sector is also actively introducing peptides with anti-aging, repair, collagen-boosting, antioxidative functionalities, with rising consumer and brand expectations for natural or bio-active, safety validated ingredients. Research and basic science needs remain stable, being driven by automation and high-throughput synthesis tools, giving academic institutions and biotech startups need for more flexible, fast, custom peptide synthesis services. Overall, downstream demand is trending toward more complex structures / high modifications / higher purity / more individualized use, and demands for faster turnaround and higher service quality.
This report aims to provide a comprehensive presentation of the global market for Peptide Synthesis, focusing on the total sales revenue, key companies market share and ranking, together with an analysis of Peptide Synthesis by region & country, by Type, and by Application.
The Peptide Synthesis market size, estimations, and forecasts are provided in terms of sales revenue ($ millions), considering 2024 as the base year, with history and forecast data for the period from 2020 to 2031. With both quantitative and qualitative analysis, to help readers develop business/growth strategies, assess the market competitive situation, analyze their position in the current marketplace, and make informed business decisions regarding Peptide Synthesis.
Market Segmentation
By Company
Segment by Type
Segment by Application
By Region
Chapter Outline
Chapter 1: Introduces the report scope of the report, global total market size. This chapter also provides the market dynamics, latest developments of the market, the driving factors and restrictive factors of the market, the challenges and risks faced by manufacturers in the industry, and the analysis of relevant policies in the industry.
Chapter 2: Detailed analysis of Peptide Synthesis company competitive landscape, revenue market share, latest development plan, merger, and acquisition information, etc.
Chapter 3: Provides the analysis of various market segments by Type, covering the market size and development potential of each market segment, to help readers find the blue ocean market in different market segments.
Chapter 4: Provides the analysis of various market segments by Application, covering the market size and development potential of each market segment, to help readers find the blue ocean market in different downstream markets.
Chapter 5: Revenue of Peptide Synthesis in regional level. It provides a quantitative analysis of the market size and development potential of each region and introduces the market development, future development prospects, market space, and market size of each country in the world.
Chapter 6: Revenue of Peptide Synthesis in country level. It provides sigmate data by Type, and by Application for each country/region.
Chapter 7: Provides profiles of key players, introducing the basic situation of the main companies in the market in detail, including product revenue, gross margin, product introduction, recent development, etc.
Chapter 8: Analysis of industrial chain, including the upstream and downstream of the industry.
Chapter 9: Conclusion.