Product Code: RA100365
ADC Contract Manufacturing Market (6th Edition): Industry Trends and Global Forecasts, till 2035 - Distribution by Stage of Development (Phase I, Phase II, Phase III and Commercial), Process Component (Antibody, HPAPI / Cytotoxic Payload, Conjugation / Linker and Fill / Finish), Target Indication (Solid Tumors, Hematological Tumors and Others), Antibody Generation (Second, Third, Fourth and Next), Antibody Origin (Humanized, Chimeric, Murine and Others), Antibody Isotype (IgG1, IgG4 and Others), Type of Payload (Auristatin, Camptothecin, DNA Topoisomerase I Inhibitor, Maytansinoid and Others), Type of Linker (Maleimide, SMCC, Tetrapeptide-based linker, Valine-citrulline and Others), and Key Geographical Regions (North America, Europe, Asia-Pacific and Rest of the World)
The ADC Contract Manufacturing Market is valued at USD 1.79 billion in 2024 growing at a CAGR of 13% during the forecast period 2024-2035.
In recent years, antibody drug conjugates (ADCs) have emerged as a powerful therapeutic approach for treating a broad spectrum of cancers, encompassing both solid tumors and hematological malignancies. These sophisticated compounds consist of an antibody chemically linked to biologically active cytotoxic agents, offering improved stability, target specificity, tumor selectivity, and pharmacokinetic properties. These attributes have spurred extensive research and development efforts aimed at advancing ADC therapies to market fruition. Presently, the ADC pipeline boasts over 260 candidates undergoing clinical evaluation, alongside 23 ADC therapeutic programs already sanctioned by regulatory bodies. The promise of such therapies in precisely targeting tumor cells while minimizing off-target toxicities has propelled their success and widespread adoption within the healthcare sector.
Nevertheless, the manufacturing process for ADCs is intricately complex, fraught with various challenges such as drug/linker side reactions, toxicity exposure, contamination risks, and scale-up difficulties. Additionally, it demands substantial expertise and cutting-edge technologies, incurring significant costs. Consequently, ADC developers often opt to outsource manufacturing operations to specialized ADC contract manufacturers. By leveraging the expertise, capabilities, and production facilities of these contract manufacturing organizations (CMOs), ADC therapy developers aim to streamline manufacturing operations while reducing costs. Notably, CMOs involved in ADC contract manufacturing are actively striving to evolve into comprehensive solution providers, addressing challenges related to technology transfer and scale-up. With the escalating demand for ADCs and the growing inclination toward outsourcing among drug developers, the ADC contract manufacturing market is poised for substantial growth in the foreseeable future.
Key Market Segments
Stage of Development
- Phase I
- Phase II
- Phase III
- Commercial
Process Component
- Antibody
- HPAPI / Cytotoxic Payload
- Conjugation / Linker
- Fill / Finish
Target Indication
- Solid Tumors
- Hematological Tumors
- Others
Antibody Generation
- Second Generation
- Third Generation
- Fourth Generation
- Next Generation
Antibody Origin
- Humanized
- Chimeric
- Murine
- Others
Antibody Isotype
Type of Payload
- Auristatin
- Camptothecin
- DNA Topoisomerase I Inhibitor
- Maytansinoid
- Others
Type of Linker
SMCC
- Tetrapeptide-based linker
- Valine-citrulline
- Others
Key Geographical Regions
- North America
- Europe
- Asia-Pacific and Rest of the World
Research Coverage:
- Insightful overview on the essential components of ADC therapeutics, the challenges associated with manufacturing of such therapies along with information on the rising trend of contract manufacturing in this segment of biopharmaceutical industry.
- An in-depth analysis of the comprehensive market landscape for ADC contract manufacturers involves evaluating various pertinent factors. These include the establishment year, company size denoted by the number of employees, headquarters location, and the range of ADC manufacturing services provided, encompassing antibody manufacturing, HPAPI and payload synthesis, linker manufacturing, conjugation, and fill/finish services. Additionally, consideration is given to the types of additional services offered, such as proof-of-concept studies, process development and scale-up, and analytical development. The scale of operation, categorized into preclinical, clinical, and commercial phases, is also a crucial aspect. Moreover, the geographic location of manufacturing facilities plays a significant role in assessing the overall landscape of ADC contract manufacturers.
- Comprehensive competitiveness analysis of ADC contract manufacturers, based on manufacturing strength (in terms of scale of operation and number of ADC manufacturing facilities), service strength (in terms of number of ADC services offered, number of additional services offered and location of ADC manufacturing facilities) and supplier strength (in terms of employee count and years of experience in this field).
- Elaborate profiles of ADC contract manufacturers (shortlisted on the basis of competitiveness analysis). Each profile provides a brief overview of the company, its financial information (if available), manufacturing services portfolio (specific to antibody drug conjugates), location of production facilities, and an insightful recent development and future outlook.
- A detailed analysis of the various expansion initiatives undertaken by ADC contract manufacturers, during the period 2019-2023, along with information on several relevant parameters, such as year of expansion, type of expansion, purpose of expansion (manufacturing, analytical / development and fill / finish), scale of operation (preclinical, clinical and commercial), location of expanded facility, type of facility and most active players (based on number of expansion initiatives).
- An analysis of the recent partnerships inked between various ADC contract manufacturers, since 2019, based on several parameters, such as year of partnership, type of partnership (acquisitions, joint ventures, licensing agreements, manufacturing agreements, mergers, product development agreements, product development and manufacturing agreements, research agreements, technology integration agreements and others), purpose of agreement, scale of operation and most active players (in terms of number of partnerships). This section also highlights the regional distribution of partnership activity in this market.
- A qualitative analysis highlighting the various factors that need to be considered by ADC developers, while deciding whether to manufacture their respective products in-house or outsource the manufacturing operation to contract service providers.
- A detailed discussion on various steps (antibody manufacturing, payload manufacturing, linker manufacturing, conjugation and fill / finish) involved in the manufacturing of ADCs, along with information on the cost requirements across each stage.
- An estimate of the overall ADC manufacturing / bioconjugation capacity (in kilograms) of ADC contract manufacturers based on information provided by various stakeholders in the public domain. The analysis highlights the distribution of global capacity by company size (small, mid-sized and large), key geographical regions (North America, Europe and Asia-Pacific) and key players (in terms of highest bioconjugation capacity).
- An overview of the current market landscape of ADCs, along with detailed analysis of the ADCs pipeline, based on several relevant parameters, such as status of development, target disease indication, therapeutic area, line of treatment, dosing frequency, type of therapy, target antigen, antibody isotype, payload / cytotoxin / warhead, type of payload and type of linker.
- An in-depth analysis of completed and ongoing clinical studies of various antibody drug conjugates, based on several relevant parameters, such as trial registration year, trial status, trial phase, enrolled patient population, type of sponsor / collaborator, target population, study design, most active industry players, and non-industry players (in terms of number of trials) and key geographical regions.
- An in-depth analysis of over 140 ADC therapy developers that are likely to partner with ADC contract manufacturers, based on several relevant parameters, such as developer strength (in terms of company size and its experience), pipeline maturity (in terms of number of drugs in pipeline, their stage of development and type of target indication) and manufacturing capabilities.
- An informed estimate of the annual commercial and clinical demand for ADC therapeutics (in kilograms) based on, based on relevant parameters, such as target patient population, dosing frequency and dose strength of approved products and clinical stage candidates.
- A detailed regional capability assessment framework comparing the key geographies, based on a number of parameters, including the number of ADC contract manufacturers, number of ADC manufacturing facilities, number of facility expansions, installed ADC bioconjugation capacity, number of registered clinical trials and demand for ADCs in that particular geographical region.
- A detailed assessment of the current market scenario (in terms of existing competition and growth opportunities) across emerging and established market segments, plotted on a 2X2 matrix.
- A detailed ADC contract manufacturing market forecast analysis in order to estimate the existing market size and future opportunity for ADC contract manufacturers over the next 12 years. Based on multiple parameters, likely adoption trends and through primary validations, we have provided an informed estimate on the market size during the forecast period 2024-2035.
- Detailed projections of the current and future opportunity within the ADC contract manufacturing market across different stages of development, such as phase I, phase II, phase III and commercial.
- Detailed projections of the current and future opportunity within antibody drug conjugates contract manufacturing market across different process components, such as antibody, HPAPI / cytotoxic payload, conjugation / linker and fill / finish.
- Detailed projections of the current and future opportunity within the ADC contract manufacturing industry across different target indications, such as solid tumors, hematological tumors and others.
- Detailed projections of the current and future opportunity within the market across different antibody generations, such as second, third, fourth and next generation.
- Detailed projections of the current and future opportunity within the ADC contract manufacturing market across different antibody origins, such as humanized, chimeric, murine and others.
- Detailed projections of the current and future opportunity within the antibody drug conjugates contract manufacturing market across different antibody isotypes, such as IgG1, IgG4 and others.
- Detailed projections of the current and future opportunity within the ADC contract manufacturing market across different types of payloads, such as auristatin, camptothecin, DNA topoisomerase I inhibitor, maytansinoid and others.
- Detailed projections of the current and future opportunity within the market across different types of linkers, such as Maleimide, SMCC, tetrapeptide-based linker, valine-citrulline and others.
- Detailed projections of the current and future opportunity within the ADC contract manufacturing industry across key geographical regions, including North America, Europe, Asia-Pacific and rest of the world.
- Detailed projections of the current and future opportunity within the commercial ADC contract manufacturing market, based on several relevant parameters such as type of component, target indications, type of generation, type of antibody origin, type of antibody isotype, type of payload, type of linker and key geographical regions.
- Detailed projections of the current and future opportunity within the clinical ADC contract manufacturing market, based on several relevant parameters such as phase of development, type of component, target indications, type of antibody origin, type of antibody isotype, type of payload, type of linker and key geographical regions.
- An in-depth analysis of the factors that can impact on the growth of ADC contract manufacturing market. It also features identification of key drivers, potential restraints, emerging opportunities, and existing challenges.
Key Benefits of Buying this Report
- The report offers market leaders and newcomers valuable insights into revenue estimations for both the overall market and its sub-segments.
- Stakeholders can utilize the report to enhance their understanding of the competitive landscape, allowing for improved business positioning and more effective go-to-market strategies.
- The report provides stakeholders with a pulse on the ADC Contract Manufacturing Market, furnishing them with essential information on significant market drivers, barriers, opportunities, and challenges.
Leading Market Companies
- AbbVie Contract Manufacturing
- Abzena
CARBOGEN AMCIS
- Catalent Pharma Solutions
- Cerbios-Pharma
- Formosa Laboratories
GBI
- Lonza
- MabPlex
- Millipore Sigma
- Piramal Pharma Solutions
- Sterling Pharma Solutions
- WuXi Biologics
TABLE OF CONTENTS
Table Of Contents
1. PREFACE
- 1.1. ADC Contract Manufacturers: Market Overview
- 1.2. Market Share Insights
- 1.3. Market Segmentation Overview
- 1.4. Key Market Insights
- 1.5. Report Coverage
- 1.6. Key Questions Answered
- 1.7. Chapter Outlines
2. RESEARCH METHODOLOGY
- 2.1. Chapter Overview
- 2.2. Research Assumptions
- 2.3. Project Methodology
- 2.4. Forecast Methodology
- 2.5. Robust Quality Control
- 2.6. Key Market Segmentations
- 2.7. Key Considerations
- 2.7.1. Demographics
- 2.7.2. Economic Factors
- 2.7.3. Government Regulations
- 2.7.4. Supply Chain
- 2.7.5. COVID Impact / Related Factors
- 2.7.6. Market Access
- 2.7.7. Healthcare Policies
- 2.7.8. Industry Consolidation
3. ECONOMIC AND OTHER PROJECT SPECIFIC CONSIDERATIONS
- 3.1. Chapter Overview
- 3.2. Market Dynamics
- 3.2.1. Time Period
- 3.2.1.1. Historical Trends
- 3.2.1.2. Current and Forecasted Estimates
- 3.2.2. Currency Coverage
- 3.2.2.1. Overview of Major Currencies Affecting the Market
- 3.2.2.2. Impact of Currency Fluctuations on the Industry
- 3.2.3. Foreign Exchange Impact
- 3.2.3.1. Evaluation of Foreign Exchange Rates and Their Impact on Market
- 3.2.3.2. Strategies for Mitigating Foreign Exchange Risk
- 3.2.4. Recession
- 3.2.4.1. Historical Analysis of Past Recessions and Lessons Learnt
- 3.2.4.2. Assessment of Current Economic Conditions and Potential Impact on the Market
- 3.2.5. Inflation
- 3.2.5.1. Measurement and Analysis of Inflationary Pressures in the Economy
- 3.2.5.2. Potential Impact of Inflation on the Market Evolution
4. EXECUTIVE SUMMARY
5. INTRODUCTION
- 5.1. Chapter Overview
- 5.2. Key Components of ADCs
- 5.2.1. Antibody
- 5.2.2. Cytotoxin (Payloads)
- 5.2.3. Linker
- 5.3. ADC Manufacturing
- 5.3.1. Key Steps
- 5.3.2. Technical Challenges
- 5.3.3. Need for Outsourcing
- 5.4. Challenges Associated with Supply Chain and Method Transfer
- 5.4.1. Growing Demand for One-Stop Shops and Integrated Service Providers
- 5.5. Selecting a CMO Partner
- 5.6. Future Perspective
6. ADC CONTRACT MANUFACTURERS: MARKET LANDSCAPE
- 6.1. Chapter Overview
- 6.2. ADC Contract Manufacturers: Overall Market Landscape
- 6.2.1. Analysis by Year of Establishment
- 6.2.2. Analysis by Company Size
- 6.2.3. Analysis by Location of Headquarters
- 6.2.4. Analysis by Type of ADC Manufacturing Service Offered
- 6.2.5. Analysis by Type of Additional Service Offered
- 6.2.6. Analysis by Scale of Operation
- 6.2.7. Analysis by Location of Manufacturing Facilities
7. COMPANY PROFILES
- 7.1. Chapter Overview
- 7.2. MabPlex
- 7.2.1. Company Overview
- 7.2.2. ADC Related Services
- 7.2.3. Manufacturing Facilities
- 7.2.4. Recent Developments and Future Outlook
- 7.3. Lonza
- 7.3.1. Company Overview
- 7.3.2. Financial Information
- 7.3.3. ADC Related Services
- 7.3.4. Manufacturing Facilities
- 7.3.5. Recent Developments and Future Outlook
- 7.4. Abzena
- 7.4.1. Company Overview
- 7.4.2. ADC Related Services
- 7.4.3. Manufacturing Facilities
- 7.4.4. Recent Developments and Future Outlook
- 7.5. GBI
- 7.5.1. Company Overview
- 7.5.2. ADC Related Services
- 7.5.3. Manufacturing Facilities
- 7.5.4. Recent Developments and Future Outlook
- 7.6. CARBOGEN AMCIS
- 7.6.1. Company Overview
- 7.6.2. ADC Related Services
- 7.6.3. Manufacturing Facilities
- 7.6.4. Recent Developments and Future Outlook
- 7.7. Millipore Sigma
- 7.7.1. Company Overview
- 7.7.2. ADC Related Offerings
- 7.7.3. Manufacturing Facilities
- 7.7.4. Recent Developments and Future Outlook
- 7.8. WuXi Biologics
- 7.8.1. Company Overview
- 7.8.2. Financial Information
- 7.8.3. ADC Related Services
- 7.8.4. Manufacturing Facilities
- 7.8.5. Recent Developments and Future Outlook
- 7.9. Catalent Pharma Solutions
- 7.9.1. Company Overview
- 7.9.2. Financial Information
- 7.9.3. ADC Related Services
- 7.9.4. Manufacturing Facilities
- 7.9.5. Recent Developments and Future Outlook
- 7.10. Cerbios-Pharma
- 7.10.1. Company Overview
- 7.10.2. ADC Related Services
- 7.10.3. Manufacturing Facilities
- 7.10.4. Recent Developments and Future Outlook
- 7.11. Formosa Laboratories
- 7.11.1. Company Overview
- 7.11.2. ADC Related Services
- 7.11.3. Manufacturing Facilities
- 7.11.4. Recent Developments and Future Outlook
- 7.12. Sterling Pharma Solutions
- 7.12.1. Company Overview
- 7.12.2. ADC Related Services
- 7.12.3. Manufacturing Facilities
- 7.12.4. Recent Developments and Future Outlook
- 7.13. Piramal Pharma Solutions
- 7.13.1. Company Overview
- 7.13.2. ADC Related Services
- 7.13.3. Manufacturing Facilities
- 7.13.4. Recent Developments and Future Outlook
- 7.14. AbbVie Contract Manufacturing
- 7.14.1. Company Overview
- 7.14.2. ADC Related Services
- 7.14.3. Manufacturing Facilities
- 7.14.4. Recent Developments and Future Outlook
8. COMPANY COMPETITIVENESS ANALYSIS
- 8.1. Chapter Overview
- 8.2. Assumptions and Key Parameters
- 8.3. Methodology
- 8.4. ADC Contract Manufacturers: Company Competitiveness Analysis
- 8.4.1. ADC Contract Manufacturers based in North America (Peer Group I)
- 8.4.2. ADC Contract Manufacturers based in Europe (Peer Group II)
- 8.4.3. ADC Contract Manufacturers based in Asia-Pacific (Peer Group III)
- 8.5. Capability Benchmarking of Top ADC Contract Manufacturers
9. ADC CONTRACT MANUFACTURERS: RECENT EXPANSIONS
- 9.1. Chapter Overview
- 9.2. ADC Contract Manufacturers: Recent Expansions
- 9.2.1. Analysis by Year of Expansion
- 9.2.2. Analysis by Type of Expansion
- 9.2.3. Analysis by Purpose of Expansion
- 9.2.4. Analysis by Scale of Operation
- 9.2.5. Analysis by Location of Expanded Facility
- 9.2.6. Most Active Players: Analysis by Number of Expansions
10. ADC CONTRACT MANUFACTURERS: PARTNERSHIPS AND COLLABORATIONS
- 10.1. Chapter Overview
- 10.2. Partnership Models
- 10.3. ADC Contract Manufacturers: Partnerships and Collaborations
- 10.3.1. Analysis by Year of Partnership
- 10.3.2. Analysis by Type of Partnership
- 10.3.3. Analysis by Purpose of Partnership
- 10.3.4. Analysis by Scale of Operation
- 10.3.5. Most Active Players: Analysis by Number of Partnerships
- 10.3.6. Analysis by Geography
- 10.3.6.1. Intercontinental and Intracontinental Agreements
- 10.3.6.2. Local and International Agreements
11. MAKE VERSUS BUY DECISION MAKING
- 11.1. Chapter Overview
- 11.2. Assumptions and Key Parameters
- 11.2.1. Scenario 1
- 11.2.2. Scenario 2
- 11.2.3. Scenario 3
- 11.2.4. Scenario 4
- 11.3. Concluding Remarks
12. VALUE CHAIN ANALYSIS
- 12.1. Chapter Overview
- 12.2. ADC Development Value Chain
- 12.3. Cost Distribution across the Value Chain
- 12.3.1. Cost Associated with Antibody Manufacturing
- 12.3.2. Cost Associated with Payload and Linker Manufacturing
- 12.3.3. Cost Associated with Conjugation
- 12.3.4. Cost Associated with Fill / Finish
13. ADC MANUFACTURING: CAPACITY ANALYSIS
- 13.1. Chapter Overview
- 13.2. Key Assumptions and Methodology
- 13.3. ADC Manufacturing: Global Installed Capacity
- 13.3.1. Analysis by Company Size
- 13.3.2. Analysis by Location of Headquarters
- 13.3.3. Analysis by Location of Manufacturing Facilities
- 13.3.3.1 Analysis by Region
- 13.3.3.2. Analysis by Country
- 13.3.4. Analysis by Key Players
14. ADC THERAPEUTICS: MARKET OVERVIEW
- 14.1. Chapter Overview
- 14.2. Antibody Drug Conjugates: Therapies Pipeline
- 14.2.1. Analysis by Status of Development
- 14.2.2. Analysis by Target Disease Indication
- 14.2.3. Analysis by Therapeutic Area
- 14.2.4. Analysis by Line of Treatment
- 14.2.5. Analysis by Dosing Frequency
- 14.2.6. Analysis by Type of Therapy
- 14.2.7. Analysis by Target Antigen
- 14.2.8. Analysis by Antibody Isotype
- 14.2.9. Analysis by Payload / Cytotoxin / Warhead
- 14.2.10. Analysis by Type of Payload
- 14.2.11. Analysis by Linker
- 14.2.12. Analysis by Type of Linker (Cleavable / Non-Cleavable)
- 14.3. Antibody Drug Conjugates: Therapies to Watch
- 14.4. Concluding Remarks
15. CLINICAL TRIAL ANALYSIS
- 15.1. Chapter Overview
- 15.2. Scope and Methodology
- 15.3. Antibody Drug Conjugates: Clinical Trial Analysis
- 15.3.1. Analysis by Trial Registration Year
- 15.3.2. Analysis by Trial Status
- 15.3.3. Analysis of Enrolled Patient Population by Trial Status
- 15.3.4. Analysis by Trial Registration Year and Trial Status
- 15.3.5. Analysis of Enrolled Patient Population by Trial Registration Year
- 15.3.6. Analysis by Trial Phase
- 15.3.7. Analysis of Enrolled Patient Population by Trial Phase
- 15.3.8. Analysis by Type of Sponsor / Collaborator
- 15.3.9. Analysis by Target Population
- 15.3.10. Analysis by Study Design
- 15.3.11. Most Active Industry Players: Analysis by Number of Trials
- 15.3.12. Most Active Non-Industry Players: Analysis by Number of Trials
- 15.3.13. Analysis of Clinical Trials by Geography
- 15.3.14. Analysis of Enrolled Patient Population by Geography
16. LIKELY PARTNER ANALYSIS
- 16.1. Chapter Overview
- 16.2. Scoring Criteria and Key Assumptions
- 16.3. Scope and Methodology
- 16.4. Potential Strategic Partners based in North America
- 16.4.1. Most Likely Partners
- 16.4.2. Likely Partners
- 16.4.3. Least Likely Partners
- 16.5. Potential Strategic Partners based in Europe
- 16.5.1. Most Likely Partners
- 16.5.2. Likely Partners
- 16.5.3. Least Likely Partners
- 16.6. Potential Strategic Partners based in Asia-Pacific and Rest of the World
- 16.6.1. Most Likely Partners
- 16.6.2. Likely Partners
- 16.6.3. Least Likely Partners
17. ADC THERAPEUTICS: DEMAND ANALYSIS
- 17.1. Chapter Overview
- 17.2. Key Assumptions and Methodology
- 17.3. ADC Therapeutics: Global Annual Demand
- 17.3.1. ADC Therapeutics: Annual Commercial Demand
- 17.3.1.1. Analysis by Target Indication
- 17.3.1.2. Analysis by Antibody Origin
- 17.3.1.3. Analysis by Antibody Isotype
- 17.3.1.4. Analysis by Type of Payload
- 17.3.1.5. Analysis by Type of Linker
- 17.3.1.6 Analysis by Key Geographical Regions
- 17.3.2. ADC Therapeutics: Annual Clinical Demand
- 17.3.2.1. Analysis by Phase of Development
- 17.3.2.2. Analysis by Target Indication
- 17.3.2.3. Analysis by Antibody Origin
- 17.3.2.4. Analysis by Antibody Isotype
- 17.3.2.5. Analysis by Type of Payload
- 17.3.2.6. Analysis by Type of Linker
- 17.3.2.7. Analysis by Key Geographical Regions
18. REGIONAL CAPABILITY ANALYSIS
- 18.1. Chapter Overview
- 18.2. Assumptions and Key Parameters
- 18.3. ADC Contract Manufacturing Capabilities in North America
- 18.4. ADC Contract Manufacturing Capabilities in Europe
- 18.5. ADC Contract Manufacturing Capabilities in Asia-Pacific and Rest of the World
19. ATTRACTIVENESS COMPETETIVENESS MATRIX
- 19.1. Chapter Overview
- 19.2. AC Matrix: Overview
- 19.2.1. Strong Business Segments
- 19.2.2. Average Business Segments
- 19.2.3. Weak Business Segments
- 19.3. AC Matrix: Analytical Methodology
- 19.4. AC Matrix: Overall ADC Contract Manufacturing Market Scenario
- 19.4.1. AC Matrix: ADC Contract Manufacturing Scenario for Type of ADC Manufacturing Service Offered
- 19.4.2. AC Matrix: ADC Contract Manufacturing Scenario for Key Geographical Regions
20. ADC CONTRACT MANUFACTURING MARKET
- 20.1. Chapter Overview
- 20.2. Key Assumptions and Methodology
- 20.3. Global ADC Therapeutics Market, Historical Trends and Forecasted Estimates, till 2035
- 20.4. Global ADC Contract Manufacturing Market, Historical Trends and Forecasted Estimates, till 2035
- 20.4.1. Scenario Analysis
- 20.5. Key Market Segmentations
21. ADC CONTRACT MANUFACTURING MARKET, BY STAGE OF DEVELOPMENT
- 21.1. Chapter Overview
- 21.2. Key Assumptions and Methodology
- 21.3. ADC Contract Manufacturing Market: Distribution by Stage of Development, 2023, 2028 and 2035
- 21.3.1. Phase I: Forecasted Estimates, till 2035
- 21.3.2. Phase II: Forecasted Estimates, till 2035
- 21.3.3. Phase III: Forecasted Estimates, till 2035
- 21.3.4. Commercial: Forecasted Estimates, till 2035
- 21.4. Data Triangulation and Validation
22. ADC CONTRACT MANUFACTURING MARKET, BY PROCESS COMPONENT
- 22.1. Chapter Overview
- 22.2. Key Assumptions and Methodology
- 22.3. ADC Contract Manufacturing Market: Distribution by Process Component, 2023, 2028 and 2035
- 22.3.1. Antibody: Forecasted Estimates, till 2035
- 22.3.2. HPAPI / Cytotoxic Payload: Forecasted Estimates, till 2035
- 22.3.3. Conjugation / Linker: Forecasted Estimates, till 2035
- 22.3.4. Fill / Finish: Forecasted Estimates, till 2035
- 22.4. Data Triangulation and Validation
23. ADC CONTRACT MANUFACTURING MARKET, BY TARGET INDICATION
- 23.1. Chapter Overview
- 23.2. Key Assumptions and Methodology
- 23.3. ADC Contract Manufacturing Market: Distribution by Target Indication, 2023, 2028 and 2035
- 23.3.1. Solid Tumors: Forecasted Estimates, till 2035
- 23.3.2. Hematological Tumors: Forecasted Estimates, till 2035
- 23.3.3. Others: Forecasted Estimates, till 2035
- 23.4. Data Triangulation and Validation
24. ADC CONTRACT MANUFACTURING MARKET, BY ANTIBODY GENERATION
- 24.1. Chapter Overview
- 24.2. Key Assumptions and Methodology
- 24.3. ADC Contract Manufacturing Market: Distribution by Antibody Generation, 2023, 2028 and 2035
- 24.3.1. Second Generation: Forecasted Estimates, till 2035
- 24.3.2. Third Generation: Forecasted Estimates, till 2035
- 24.3.3. Fourth Generation: Forecasted Estimates, till 2035
- 24.3.4. Next Generation: Forecasted Estimates, till 2035
- 24.4. Data Triangulation and Validation
25. ADC CONTRACT MANUFACTURING MARKET, BY ANTIBODY ORIGIN
- 25.1. Chapter Overview
- 25.2. Key Assumptions and Methodology
- 25.3. ADC Contract Manufacturing Market: Distribution by Antibody Origin, 2023, 2028 and 2035
- 25.3.1. Human Origin: Forecasted Estimates, till 2035
- 25.3.2. Chimeric Origin: Forecasted Estimates, till 2035
- 25.3.3. Murine Origin: Forecasted Estimates, till 2035
- 25.3.4. Others: Forecasted Estimates, till 2035
- 25.4. Data Triangulation and Validation
26. ADC CONTRACT MANUFACTURING MARKET, BY ANTIBODY ISOTYPE
- 26.1. Chapter Overview
- 26.2. Key Assumptions and Methodology
- 26.3. ADC Contract Manufacturing Market: Distribution by Antibody Isotype, 2023, 2029 and 2035
- 26.3.1. IgG1: Forecasted Estimates, till 2035
- 26.3.2. IgG4: Forecasted Estimates, till 2035
- 26.3.3. Others: Forecasted Estimates, till 2035
- 26.4. Data Triangulation and Validation
27. ADC CONTRACT MANUFACTURING MARKET, BY TYPE OF PAYLOAD
- 27.1. Chapter Overview
- 27.2. Key Assumptions and Methodology
- 27.3. ADC Contract Manufacturing Market: Distribution by Type of Payload, 2023, 2029 and 2035
- 27.3.1. Camptothecin: Forecasted Estimates, till 2035
- 27.3.2. Maytansinoid: Forecasted Estimates, till 2035
- 27.3.3. Auristatin: Forecasted Estimates, till 2035
- 27.3.4. DNA topoisomerase I inhibitor: Forecasted Estimates, till 2035
- 27.3.5. Others: Forecasted Estimates, till 2035
- 27.4. Data Triangulation and Validation
28. ADC CONTRACT MANUFACTURING MARKET, BY TYPE OF LINKER
- 28.1. Chapter Overview
- 28.2. Key Assumptions and Methodology
- 28.3. ADC Contract Manufacturing Market: Distribution by Type of Linker, 2023, 2029 and 2035
- 28.3.1. Maleimide: Forecasted Estimates, till 2035
- 28.3.2. SMCC: Forecasted Estimates, till 2035
- 28.3.3. Tetrapeptide-based linker: Forecasted Estimates, till 2035
- 28.3.4. Valine-citrulline: Forecasted Estimates, till 2035
- 28.3.5. Others: Forecasted Estimates, till 2035
- 28.4. Data Triangulation and Validation
29. ADC CONTRACT MANUFACTURING MARKET, BY KEY GEOGRAPHICAL REGIONS
- 29.1. Chapter Overview
- 29.2. Key Assumptions and Methodology
- 29.3. ADC Contract Manufacturing Market: Distribution by Key Geographical Regions, 2023, 2029 and 2035
- 29.3.1. North America: Forecasted Estimates, till 2035
- 29.3.2. Europe: Forecasted Estimates, till 2035
- 29.3.3. Asia-Pacific and Rest of the World: Forecasted Estimates, till 2035
- 29.4. Data Triangulation and Validation
30. COMMERCIAL ADC CONTRACT MANUFACTURING MARKET
- 30.1. Chapter Overview
- 30.2. Key Assumptions and Methodology
- 30.3. Commercial ADC Contract Manufacturing Market, Forecasted Estimates, till 2035
- 30.3.1. Commercial ADC Contract Manufacturing Market: Distribution by Process Component, Forecasted Estimates, till 2035
- 30.3.2. Commercial ADC Contract Manufacturing Market: Distribution by Target Indication, Forecasted Estimates, till 2035
- 30.3.3. Commercial ADC Contract Manufacturing Market: Distribution by Antibody Generation, Forecasted Estimates, till 2035
- 30.3.4. Commercial ADC Contract Manufacturing Market: Distribution by Antibody Origin, Forecasted Estimates, till 2035
- 30.3.5. Commercial ADC Contract Manufacturing Market: Distribution by Antibody Isotype, Forecasted Estimates, till 2035
- 30.3.6. Commercial ADC Contract Manufacturing Market: Distribution by Type of Payload, Forecasted Estimates, till 2035
- 30.3.7. Commercial ADC Contract Manufacturing Market: Distribution by Type of Linker, Forecasted Estimates, till 2035
- 30.3.8. Commercial ADC Contract Manufacturing Market: Distribution by Key Geographical Regions, Forecasted Estimates, till 2035
- 30.4. Data Triangulation and Validation
31. CLINICAL ADC CONTRACT MANUFACTURING MARKET
- 31.1. Chapter Overview
- 31.2. Key Assumptions and Methodology
- 31.3. Clinical ADC Contract Manufacturing Market, Forecasted Estimates, till 2035
- 31.3.1. Clinical ADC Contract Manufacturing Market: Distribution by Phase of Development, Forecasted Estimates, till 2035
- 31.3.2. Clinical ADC Contract Manufacturing Market: Distribution by Process Component, Forecasted Estimates, till 2035
- 31.3.3. Clinical ADC Contract Manufacturing Market: Distribution by Target Indication, Forecasted Estimates, till 2035
- 31.3.4. Clinical ADC Contract Manufacturing Market: Distribution by Antibody Origin, Forecasted Estimates, till 2035
- 31.3.5. Clinical ADC Contract Manufacturing Market: Distribution by Antibody Isotype, Forecasted Estimates, till 2035
- 31.3.6. Clinical ADC Contract Manufacturing Market: Distribution by Type of Payload, Forecasted Estimates, till 2035
- 31.3.7. Clinical ADC Contract Manufacturing Market: Distribution by Type of Linker, Forecasted Estimates, till 2035
- 31.3.8. Clinical ADC Contract Manufacturing Market: Distribution by Key Geographical Regions, Forecasted Estimates, till 2035
- 31.4. Data Triangulation and Validation
32. MARKET IMPACT ANALYSIS: DRIVERS, RESTRAINTS, OPPORTUNITIES AND CHALLENGES
- 32.1. Chapter Overview
- 32.2. Market Drivers
- 32.3. Market Restraints
- 32.4. Market Opportunities
- 32.5. Market Challenges
- 32.6. Conclusion
33. CONCLUDING REMARKS
34. INTERVIEW TRANSCRIPTS
35. APPENDIX I: TABULATED DATA
36. APPENDIX II: LIST OF COMPANIES AND ORGANIZATIONS