原位杂合反应(ISH) 市场规模、份额和成长分析（按产品、技术、应用、最终用户和地区）：产业预测 (2025-2032)

2023年全球原位杂合反应（ISH）市场规模预计为21亿美元，从2024年的23.6亿美元增长到2032年的60.6亿美元，预测期间（2025年-2032年）预计复合年增长率为12.5 % 。

原位杂合反应(ISH) 市场由于其在分子诊断、基因编辑和重组 DNA 技术中的关键作用而正在经历显着增长。该技术可以对细胞和组织内的核酸进行定位和定量，并提供高灵敏度和准确性。已应用于分子生物学、免疫学、发育生物学、血液病理学等多个领域，特别提高了在疾病预后、药物发现、生物标记开发等领域的研究能力。近年来，大量的研究和开发工作致力于高性能、经济高效和快速多重技术的创新，例如 PLISH（邻近连接原位杂交）。这些进步有助于更深入了解细胞功能，进一步促进市场扩张。

目录

介绍

• 分析目的
• 市场范围
• 定义

分析方法

• 资讯采购
• 次要/主要资料方法
• 市场规模预测
• 市场假设与约束

执行摘要

• 市场概况及展望
• 供需趋势分析
• 按细分市场的机会分析

市场动态及前景

• 市场概况
• 市场规模
• 市场动态
  • 驱动因素和机会
  • 抑制因素和挑战
• 波特分析

主要市场考虑因素

• 关键成功因素
• 竞争程度
• 主要投资机会
• 市场生态系统
• 市场魅力指数（2024年）
• PESTEL分析
• 总体经济指标
• 价值链分析
• 价格分析
• 技术分析
• 监管分析
• 专利分析
• 案例研究

全球原位杂合反应(ISH) 市场规模与复合年增长率：按产品分类（2025-2032 年）

• 市场概况
• 消耗品
  • 探测
  • 试剂套件/试剂
  • 配件
• 装置
• 软体

全球原位杂合反应(ISH) 市场规模与复合年增长率：按技术划分（2025-2032 年）

• 市场概况
• 萤光原位杂合反应
  • DNA萤光原位杂合反应
  • RNA萤光原位杂合反应
  • PNA萤光原位杂合反应
• 显色原位杂合反应

全球原位杂合反应（ISH）市场规模与复合年增长率：按应用分类（2025-2032）

• 市场概况
• 癌症诊断
• 细胞学
• 感染疾病诊断
• 神经科学
• 免疫学

全球原位杂合反应(ISH) 市场规模与复合年增长率：按最终用户划分（2025-2032 年）

• 市场概况
• 医院/诊断实验室
• 学术研究所

全球原位杂合反应（ISH）市场规模与复合年增长率（2025-2032）

• 北美洲
  • 美国
  • 加拿大
• 欧洲
  • 德国
  • 西班牙
  • 法国
  • 英国
  • 义大利
  • 其他欧洲国家地区
• 亚太地区
  • 中国
  • 印度
  • 日本
  • 韩国
  • 其他亚太地区
• 拉丁美洲
  • 巴西
  • 其他拉丁美洲地区
• 中东/非洲
  • 海湾合作委员会国家
  • 南非
  • 其他中东/非洲

竞争格局

• 前5名企业对比
• 主要企业市场定位（2024年）
• 主要企业采取的策略
• 近期市场趋势
• 主要企业市场占有率（2024年）
• 主要企业简介
  • 公司简介
  • 产品系列分析
  • 按细分市场分類的份额分析
  • 收益与前一年同期比较（2022-2024）

主要企业简介

• 雅培（美国）
• F. Hoffmann-La Roche AG（瑞士）
• 赛默飞世尔科技公司（美国）
• 丹纳赫（美国）
• 安捷伦科技公司（美国）
• Biocare Medical, LLC（美国）
• Bio-Techne 公司（美国）
• QIAGEN NV（荷兰）
• 默克公司（德国）
• 珀金埃尔默（美国）
• 恩佐生物化学（美国）
• Bio-Rad 实验室（美国）
• 上元科技股份有限公司 (中国台湾地区)
• BioGenex 实验室（美国）
• OpGen（美国）
• 生物 SB（美国）
• Abcam (UK)
• Zytomed 系统有限公司（德国）
• NeoGenomics 实验室（美国）
• BioView（以色列）

结论和建议

Global In Situ Hybridization ISH Market size was valued at USD 2.1 billion in 2023 and is poised to grow from USD 2.36 billion in 2024 to USD 6.06 billion by 2032, growing at a CAGR of 12.5% during the forecast period (2025-2032).

The market for in-situ hybridization (ISH) is experiencing significant growth due to its pivotal role in molecular diagnostics, gene editing, and recombinant DNA technology. This technique allows for the localization and quantification of nucleic acids within cells and tissues, offering high sensitivity and accuracy. Its application across diverse fields, including molecular biology, immunology, developmental biology, and hematopathology, has enhanced research capabilities, particularly in disease prognosis, drug discovery, and biomarker development. Over the past few years, substantial R&D efforts have been made to innovate technologies like Proximity Ligation in situ Hybridization, which boasts high performance, cost-effectiveness, and rapid multiplexing. Such advancements are fostering a deeper understanding of cellular functions, further driving market expansion.

Top-down and bottom-up approaches were used to estimate and validate the size of the Global In Situ Hybridization ISH Market and to estimate the size of various other dependent submarkets. The research methodology used to estimate the market size includes the following details: The key players in the market were identified through secondary research, and their market shares in the respective regions were determined through primary and secondary research. This entire procedure includes the study of the annual and financial reports of the top market players and extensive interviews for key insights from industry leaders such as CEOs, VPs, directors, and marketing executives. All percentage shares split, and breakdowns were determined using secondary sources and verified through Primary sources. All possible parameters that affect the markets covered in this research study have been accounted for, viewed in extensive detail, verified through primary research, and analyzed to get the final quantitative and qualitative data.

Global In Situ Hybridization ISH Market Segmental Analysis

Global In Situ Hybridization ISH Market is segmented by Product, Technology, Application, End-User and region. Based on Product, the market is segmented into Consumables, Instruments andSoftware. Based on Technology, the market is segmented into Fluorescent In Situ Hybridization and Chromogenic in Situ Hybridization. Based on Application, the market is segmented into Cancer Diagnostics, Cytology, Infectious Disease Diagnostics, Neuroscience and Immunology. Based on End-User, the market is segmented into Hospitals and Diagnostic Laboratories and Academic & Research Institutes. Based on region, the market is segmented into North America, Europe, Asia Pacific, Latin America and Middle East & Africa.

Driver of the Global In Situ Hybridization ISH Market

The Global In Situ Hybridization (ISH) market is primarily driven by the alarming rise in cancer cases worldwide over recent years. Extensive research has unveiled recurrent genomic abnormalities as key contributors to various cancers. By integrating cytogenetic assays like ISH with DNA fluorescence in situ hybridization (FISH) and immunohistochemistry (IHC), researchers are now armed with advanced diagnostic tools that enhance their capabilities in cancer studies. Direct imaging of gene expression at the RNA level sheds light on the dynamics between cancer cells and their microenvironment, facilitating the evolution of diagnostic approaches. According to GLOBOCAN, the projected surge in cancer cases-estimated to reach 29.5 million globally by 2040-alongside the sharp increase in hemophilia incidences, underscores the pressing need for innovative diagnostic solutions. The escalating demand for ISH techniques in laboratories for chromosomal abnormalities and infectious disease diagnosis further propels market growth, alongside rising health expenditures and the prevalence of chronic illnesses like cancer and Alzheimer's disease.

Restraints in the Global In Situ Hybridization ISH Market

The Global In Situ Hybridization (ISH) market faces significant restraints that may hinder revenue growth. Short-lived fluorophore molecules present challenges, as the fluorescence signal diminishes rapidly over time, making fluorescence in situ hybridization (FISH) a time-sensitive technique. Additionally, FISH struggles with the detection of unbalanced translocations and low clonal cell populations in cases of minimal residual disease after cancer treatment. Further limitations include its reduced sensitivity compared to immunohistochemistry, relatively fewer false-positive results, and the risk of sample contamination during PCR processes. As a result, ISH is becoming less favored for diagnosing diseases with low pathogen loads due to its high detection threshold.

Market Trends of the Global In Situ Hybridization ISH Market

The Global In Situ Hybridization (ISH) market is witnessing a dynamic upward trend driven by advancements aimed at enhancing sensitivity and specificity in hybridization techniques. Innovations such as strand displacement amplification and molecular beacons are broadening the applications of ISH across research and diagnostic settings. These technologies enable the precise detection of low copy number nucleic acids, making them invaluable in fields like oncology, genetics, and infectious disease testing. As the demand for accurate and early diagnostics rises, coupled with increasing investments in research initiatives, the ISH market is poised for significant growth, reflecting its critical role in molecular biology and pathology.

Table of Contents

Introduction

• Objectives of the Study
• Scope of the Report
• Definitions

Research Methodology

• Information Procurement
• Secondary & Primary Data Methods
• Market Size Estimation
• Market Assumptions & Limitations

Executive Summary

• Global Market Outlook
• Supply & Demand Trend Analysis
• Segmental Opportunity Analysis

Market Dynamics & Outlook

• Market Overview
• Market Size
• Market Dynamics
  • Drivers & Opportunities
  • Restraints & Challenges
• Porters Analysis
  • Competitive rivalry
  • Threat of substitute
  • Bargaining power of buyers
  • Threat of new entrants
  • Bargaining power of suppliers

Key Market Insights

• Key Success Factors
• Degree of Competition
• Top Investment Pockets
• Market Ecosystem
• Market Attractiveness Index, 2024
• PESTEL Analysis
• Macro-Economic Indicators
• Value Chain Analysis
• Pricing Analysis
• Technology Analysis
• Regulatory Analysis
• Patent Analysis
• Case Studies

Global In Situ Hybridization ISH Market Size by Product & CAGR (2025-2032)

• Market Overview
• Consumables
  • Probes
  • Kits & Reagents
  • Accessories
• Instruments
• Software

Global In Situ Hybridization ISH Market Size by Technology & CAGR (2025-2032)

• Market Overview
• Fluorescent In Situ Hybridization
  • DNA Fluorescent in Situ Hybridization
  • RNA Fluorescent in Situ Hybridization
  • PNA Fluorescent in Situ Hybridization
• Chromogenic in Situ Hybridization

Global In Situ Hybridization ISH Market Size by Application & CAGR (2025-2032)

• Market Overview
• Cancer Diagnostics
• Cytology
• Infectious Disease Diagnostics
• Neuroscience
• Immunology

Global In Situ Hybridization ISH Market Size by End-User & CAGR (2025-2032)

• Market Overview
• Hospitals and Diagnostic Laboratories
• Academic & Research Institutes

Global In Situ Hybridization ISH Market Size & CAGR (2025-2032)

• North America (Product, Technology, Application, End-User)
  • US
  • Canada
• Europe (Product, Technology, Application, End-User)
  • Germany
  • Spain
  • France
  • UK
  • Italy
  • Rest of Europe
• Asia Pacific (Product, Technology, Application, End-User)
  • China
  • India
  • Japan
  • South Korea
  • Rest of Asia-Pacific
• Latin America (Product, Technology, Application, End-User)
  • Brazil
  • Rest of Latin America
• Middle East & Africa (Product, Technology, Application, End-User)
  • GCC Countries
  • South Africa
  • Rest of Middle East & Africa

Competitive Intelligence

• Top 5 Player Comparison
• Market Positioning of Key Players, 2024
• Strategies Adopted by Key Market Players
• Recent Developments in the Market
• Company Market Share Analysis, 2024
• Company Profiles of All Key Players
  • Company Details
  • Product Portfolio Analysis
  • Company's Segmental Share Analysis
  • Revenue Y-O-Y Comparison (2022-2024)

Key Company Profiles

• Abbott (US)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• F. Hoffmann-La Roche AG (Switzerland)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Thermo Fisher Scientific Inc. (US)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Danaher (US)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Agilent Technologies, Inc. (US)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Biocare Medical, LLC (US)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Bio-Techne Corporation (US)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• QIAGEN N.V. (Netherlands)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Merck KGaA (Germany)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• PerkinElmer (US)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Enzo Biochem (US)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Bio-Rad Laboratories (US)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Abnova Corporation (Taiwan)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• BioGenex Laboratories (US)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• OpGen (US)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Bio SB (US)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Abcam (UK)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Zytomed Systems GmbH (Germany)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• NeoGenomics Laboratories (US)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• BioView (Israel)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments

Conclusion & Recommendations