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市场调查报告书
商品编码
1679286
2030 年小鼠模型市场预测:按模型类型、技术、适应症、应用、最终用户和地区进行的全球分析Mice Model Market Forecasts to 2030 - Global Analysis By Model Type, Technology, Indication, Application, End User and By Geography |
根据 Stratistics MRC 的数据,全球小鼠模型市场预计在 2024 年将达到 15 亿美元,到 2030 年将达到 27 亿美元,预测期内的复合年增长率为 10.1%。小鼠模型由于小鼠与人类基因相似而成为研究人类疾病、生物过程和药物开发的实验工具。这些模型可帮助研究人员研究癌症、神经退化性疾病和心血管疾病等病症。有各种各样的近交、杂交、转基因、敲除和人源化模型可供选择,每种模型都可以满足特定的研究需求。 CRISPR-Cas9 和其他基因编辑技术正在提高这些模型针对疾病研究的精确度。
药物研发对可靠的临床前模型的需求日益增加
製药和生物技术公司广泛使用小鼠模型在临床试验前评估药物功效和毒性,从而降低人体研究的失败率。小鼠的生殖週期短,且基因与人类相似,非常适合进行快速、可扩展的实验。 FDA 和 EMA 等监管机构要求提供大量的临床前证据,这进一步推动了生物医学研究中对小鼠模型的需求。癌症和神经系统疾病等慢性疾病的增加推动了对用于治疗研究的复杂小鼠模型的需求。
道德问题和严格的动物试验规定
PETA 和 HSUS 等动物权利组织积极反对在研究中使用动物模型,并提倡使用替代技术。研究机构必须支付更多费用来遵守有关动物试验的严格规定,例如美国《动物福利法》和欧盟的《REACH》。此外,公众压力和企业减少动物试验的承诺导致更多资金被投入到替代模型上,如类器官、In Silico模拟和人体晶片技术,从而阻碍了市场成长。
尖端基因改造技术开发
CRISPR-Cas9等现代基因改造方法大大提高了用于疾病研究的小鼠模型的准确性。科学家能够精确地创建敲除、敲入和人源化小鼠模型,以便更好地为阿兹海默症、癌症和自体免疫疾病等疾病建立疾病模型。製药公司、生物技术公司和研究机构之间的合作也推动了用于药物测试和治疗方法突破的客製化小鼠模型的创新。
基因工程模型高成本
培育、饲养和专门照顾基因改造和基因敲除小鼠的需求增加了研究成本。这种成本负担通常会限制学术机构和小型实验室获得先进的小鼠模型。此外,基因改造模型的长期开发时间可能会推迟重要的研究项目,从而增加更便宜的替代品的吸引力。随着 3D 细胞培养和人工智慧主导的药物开发等替代研究技术的日益普及,小鼠模型的不断增长的市场也受到了威胁。
COVID-19 的影响
COVID-19 疫情最初扰乱了实验动物供应链,影响了研究时间表和临床前测试活动。封锁和旅行限制推迟了育种计划并限制了研究设施的使用,阻碍了一系列生物医学研究。但这场疫情也凸显了小鼠模型在疫苗和抗病毒药物开发中的重要性。人们对感染疾病模型的日益关注正推动对小鼠模型市场的重新投资,为其长期成长做好准备。
预测期内,近交系小鼠市场预计将占最大份额
预计在预测期内,近交系小鼠将占据最大的市场占有率,因为基因的一致性保证了生物医学研究的可重复性和一致性。该类小鼠广泛应用于癌症研究、免疫学研究、毒理学测试等,并受到製药和学术机构的青睐。此外,个人化医疗对可靠的临床前模型的需求不断增长,进一步推动了近交系小鼠的采用。
预测期内,肿瘤学领域预计将以最高复合年增长率成长
由于全球癌症负担不断增加以及对癌症研究先进临床前模型的需求不断增长,预计肿瘤学领域将在预测期内呈现最高的成长率。小鼠模型在研究肿瘤生物学、测试新型癌症治疗方法以及临床试验前评估免疫疗法的疗效方面发挥重要作用。随着研究人员寻求模拟人类肿瘤微环境的精确模型,对基因工程小鼠 (GEM)、患者来源异种移植 (PDX) 模型和人性化小鼠的需求正在激增。
在预测期内,预计北美将占据最大的市场占有率,这得益于其完善的研究基础设施、对生物医学研究的高投入以及製药公司的强大影响力。美国在临床前研究方面处于领先地位,大量资金来自美国国立卫生研究院 (NIH) 和私人生物技术公司等组织。该地区对药物研发的兴趣日益浓厚,再加上先进的基因工程能力,继续推动对小鼠模型的需求。
预计预测期内亚太地区将呈现最高的复合年增长率。这是由于中国、日本和印度等国家的政府对生物医学研究的支持不断增加、医疗成本不断上升以及製药业的扩张。此外,基因编辑技术的进步使得基因转殖小鼠的使用率不断提高。亚洲研究机构与全球製药公司之间的合作研究正在进一步推动该地区的市场扩张。
According to Stratistics MRC, the Global Mice Model Market is accounted for $1.5 billion in 2024 and is expected to reach $2.7 billion by 2030 growing at a CAGR of 10.1% during the forecast period. A mice model is a laboratory tool used to study human diseases, biological processes, and drug development due to mice's genetic similarity to humans. These models help researchers investigate conditions like cancer, neurodegenerative disorders, and cardiovascular diseases. Different types include inbred, outbred, transgenic, knockout, and humanized models, each serving specific research needs. CRISPR-Cas9 and other gene-editing technologies have enhanced the precision of these models for targeted disease studies.
Growing need for reliable preclinical models in drug discovery and development
The probability of failure in human research is decreased by the widespread use of mouse models by pharmaceutical and biotechnology companies to assess medication effectiveness and toxicity prior to clinical trials. Mice are perfect for quick and scalable experiments because of their short reproductive cycle and genetic resemblance to humans. The need for mouse models in biomedical research is further increased by regulatory bodies like the FDA and EMA, which want substantial preclinical evidence. The need for sophisticated mouse models for therapeutic research has increased due to the growth in chronic illnesses, such as cancer and neurological disorders.
Ethical concerns and stringent animal testing regulations
Animal rights groups like PETA and HSUS aggressively oppose the use of animal models in research and promote the use of alternative techniques. Research institutes must pay more to comply with strict regulations on animal testing, such as the Animal Welfare Act in the United States and the European Union's REACH. Additionally, there is now more money being spent on alternative models including organoids, in silico simulations, and human-on-a-chip technologies as a result of public pressure and business pledges to decrease animal experimentation hampers the market growth.
Development of cutting-edge genetic modification techniques
Modern genetic alteration methods, such CRISPR-Cas9, have greatly increased the accuracy of mouse models used in illness research. Better disease modeling for diseases like Alzheimer's, cancer, and autoimmune illnesses is now possible because to scientists' ability to accurately generate knockout, knock-in, and humanized mouse models. Collaborations among pharmaceutical corporations, biotech businesses, and research institutes are also encouraging innovation in the creation of customized mouse models for drug testing and therapeutic breakthroughs.
High costs associated with genetically engineered models
Higher research costs are a result of the breeding, housing, and specialized care needed for transgenic and knockout mice. The cost burden frequently prevents university institutions and small research labs from having access to sophisticated mouse models. Additionally, the lengthy development periods for genetically modified models may cause important research initiatives to be postponed, increasing the appeal of less expensive alternatives. The market expansion for mouse models is also threatened by the growing availability of alternative research techniques like 3D cell cultures and AI-driven drug development.
Covid-19 Impact
The COVID-19 pandemic initially disrupted the supply chain for laboratory animals, affecting research timelines and preclinical testing activities. Lockdowns and travel restrictions led to delays in breeding programs and limited access to research facilities, slowing down various biomedical studies. However, the pandemic also highlighted the importance of mice models in vaccine and antiviral drug development. This increased focus on infectious disease models has driven renewed investments in the mice model market, positioning it for long-term growth.
The inbred mice segment is expected to be the largest during the forecast period
The inbred mice segment is expected to account for the largest market share during the forecast period due to its genetic uniformity, which ensures reproducibility and consistency in biomedical research. These mice are extensively used in cancer research, immunology studies, and toxicology testing, making them a preferred choice for pharmaceutical and academic institutions. Additionally, the increasing demand for reliable preclinical models in personalized medicine is further driving the adoption of inbred mice.
The oncology segment is expected to have the highest CAGR during the forecast period
Over the forecast period, the oncology segment is predicted to witness the highest growth rate due to the rising global burden of cancer and the increasing need for advanced preclinical models for cancer research. Mice models play a crucial role in studying tumor biology, testing novel cancer therapies, and evaluating the efficacy of immunotherapies before clinical trials. The demand for genetically engineered mice (GEMs), patient-derived xenograft (PDX) models, and humanized mice has surged as researchers seek accurate models to mimic human tumor microenvironments.
During the forecast period, the North America region is expected to hold the largest market share owing to its well-established research infrastructure, high investments in biomedical research, and strong presence of pharmaceutical companies. The U.S. leads in preclinical research, with extensive funding from organizations like the National Institutes of Health (NIH) and private biotech firms. The region's growing focus on drug discovery, coupled with advanced genetic engineering capabilities, continues to drive demand for mice models.
Over the forecast period, the Asia Pacific region is anticipated to exhibit the highest CAGR attributed to increasing government support for biomedical research, rising healthcare expenditures, and expanding pharmaceutical industries in countries like China, Japan, and India. Additionally, the adoption of genetically modified mice models is increasing, driven by advancements in gene-editing technologies. Collaborations between Asian research institutes and global pharmaceutical companies are further fueling market expansion in this region.
Key players in the market
Some of the key players in Mice Model market include Allentown LLC, Charles River Laboratories International, Inc., Cyagen Biosciences Inc, Envigo, genOway S.A., Harbour Biomed, Hera Biolabs, Inotiv, Janvier Labs, Ozgene Pty Ltd, PolyGene, Sage Labs, Taconic Biosciences, Inc., The Jackson Laboratory, Trans Genic Inc. and TransCure bioServices .
In February 2025, HBM Alpha Therapeutics Inc., an innovative biotechnology company incubated by Harbour BioMed, announced a strategic collaboration and license agreement with a business partner to advance novel therapies targeting corticotropin-releasing hormone for various disorders.
In February 2025, Harbour BioMed and Insilico Medicine achieved strategic collaboration to advance AI-driven antibody discovery and development. leveraging their respective technological strengths in antibody discovery and artificial intelligence.
Note: Tables for North America, Europe, APAC, South America, and Middle East & Africa Regions are also represented in the same manner as above.