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市场调查报告书
商品编码
1871424
2021-2031年欧洲体外微电极阵列市场报告:范围、细分、动态和竞争分析Europe Microelectrode Array In Vitro Market Report 2021-2031 by Scope, Segmentation, Dynamics, and Competitive Analysis |
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2023 年欧洲微电极阵列 (MEA) 体外市场价值约为 449 万美元,预计到 2031 年将成长至 651 万美元,在此期间的年复合成长率(CAGR) 为 4.7%。
推动这一市场发展的重要因素之一是人们越来越重视开发动物试验模型的替代方案。虽然动物模型传统上被用于生物医学研究,以研究人类特有的疾病,但由于人类和动物药物代谢有显着差异,它们往往无法准确预测人类对药物的反应。这种差异导致人们逐渐认识到,动物模型可能并不适用于所有类型的药物毒性研究。此外,在国际零残忍组织(Cruelty-Free International)和医学实验动物替代基金会(Fund for the Replacement of Animals in Medical Experiments)等倡导减少动物试验的组织的推动下,欧洲和北美近期出台的法规对动物试验的使用施加了更严格的限制。这些监管变化正在推动微电极阵列在体外试验中的应用,尤其是在製药和生物技术领域,这些领域迫切需要更可靠的方法来评估药物的神经毒性和心臟毒性。
像BMSEED这样的製造商处于这项创新的前沿,提供诸如专有的可拉伸微电极阵列(sMEA)和MEASSuRE平台等先进产品。 sMEA旨在复製细胞的电学和力学环境,从而高度模拟体内条件。这种仿生法提高了体外实验的有效性,在临床前研究早期阶段就能提供更准确、更贴近人体的资料,这有助于降低人体临床试验中常见的高失败率。
欧洲体外微电极阵列市场按国家、产品和应用进行细分。本分析涵盖的国家包括英国、德国、法国、义大利、西班牙以及欧洲其他地区。市场主要参与者正专注于策略发展,微电极阵列在研究中的日益普及,以及政府旨在改善医疗保健和医学研究基础设施的倡议,预计将推动市场成长。
德国在微电极阵列市场中处于领先地位,以其在神经生物学、心臟病学和药物研发等领域的先进诊断工具和研究应用方面的卓越品质和创新而闻名。包括MaxWell Biosystems、Multi-Channel Systems和BMSEED在内的德国知名企业正积极进行研发,推出包括3D和CMOS技术在内的创新微电极阵列解决方案。此外,德国还实施了严格的动物实验法规,这为向体外模型、类器官和晶片器官等替代测试技术的过渡提供了支持。
例如,位于图宾根的3R中心因其开发器官晶片系统以替代动物实验而荣获2024年乌苏拉·M·汉德尔动物福利奖,彰显了其对创新研究的投入。此外,明斯特马克斯·普朗克分子生物医学研究所的研究人员开发了一种新型网状微电极阵列,可促进脑类器官的生长和电生理分析,这对于研究阿兹海默症和帕金森氏症等疾病至关重要。在领先企业、先进研究机构和政府政策的支持下,德国市场可望显着成长。
从市场细分来看,欧洲体外微电极阵列市场按产品类型、应用和国家/地区进行分类。产品类型包括传统微电极阵列 (MEA)、多孔微电极阵列 (microwell-MEA) 和 CMOS 微电极阵列 (CMOS-MEA),其中多孔微电极阵列在 2023 年占据最大的市场份额。从应用来看,市场分为心肌细胞、神经和其他类别,心肌细胞应用也占据领先的市场。
微电极阵列体外市场的主要参与者包括Tucker Davis Technologies、SCREEN Holdings Co., Ltd.、Plexon Inc.、MaxWell Biosystems AG、Harvard Bioscience Inc.、Axion BioSystems Inc.、3Brain AG、NeuroNexus Technologies Inc.、MicroElectrodeDevices Inc.、Blackcocoon、NeuroNexus Technologies Inc。这些公司在推动该地区微电极阵列技术的开发和应用方面发挥着至关重要的作用。
The Europe microelectrode array (MEA) in vitro market was valued at approximately US$ 4.49 million in 2023 and is projected to grow to US$ 6.51 million by 2031, reflecting a compound annual growth rate (CAGR) of 4.7% during this period.
A significant driver of this market is the increasing emphasis on developing alternatives to animal testing models. While animal models have traditionally been used in biomedical research to study human-specific diseases, they often fail to accurately predict human drug responses due to substantial differences in drug metabolism between humans and animals. This discrepancy has led to a growing recognition that animal models may not be suitable for all types of drug toxicity studies. Furthermore, recent regulations in Europe and North America have imposed stricter limitations on the use of animals in research, driven by organizations such as Cruelty-Free International and the Fund for the Replacement of Animals in Medical Experiments, which advocate for the reduction of animal testing. These regulatory changes are propelling the adoption of microelectrode arrays for in vitro testing, particularly in the pharmaceutical and biotechnology sectors, where there is a push for more reliable methods to assess neurotoxicity and cardiotoxicity of drugs.
Manufacturers like BMSEED are at the forefront of this innovation, offering advanced products such as proprietary stretchable microelectrode arrays (sMEAs) and the MEASSuRE platform. The sMEAs are designed to replicate the electrical and mechanical environments of cells, closely mimicking in vivo conditions. This biomimetic approach enhances the validity of in vitro experiments, providing more accurate and human-relevant data early in the preclinical research phase, which can help reduce the high failure rates seen in human clinical trials.
The microelectrode array in vitro market in Europe is segmented by country, product, and application. The countries included in this analysis are the UK, Germany, France, Italy, Spain, and the Rest of Europe. Key players in the market are focusing on strategic developments, and the increasing use of microelectrode arrays in research, along with government initiatives aimed at improving healthcare and medical research infrastructure, are expected to drive market growth.
Germany stands out as a leader in the microelectrode array market, known for its quality and innovation in advanced diagnostic tools and research applications in fields such as neurobiology, cardiology, and drug discovery. Prominent companies in Germany, including MaxWell Biosystems, Multi-Channel Systems, and BMSEED, are actively engaged in R&D to introduce innovative microelectrode array solutions, including 3D and CMOS technologies. The country has also implemented stringent regulations regarding animal testing in biotechnology and pharmaceutical research, which supports the transition to alternative testing technologies like in vitro models, organoids, and organ-on-chips.
For instance, the 3R Center in Tubingen was awarded the Ursula M. Handel Animal Welfare Prize 2024 for its development of organ-on-chip systems as alternatives to animal testing, highlighting the commitment to innovative research. Additionally, researchers from the Max Planck Institute for Molecular Biomedicine in Munster have developed a novel mesh microelectrode array that enhances the growth and electrophysiological analysis of brain organoids, which are crucial for studying diseases like Alzheimer's and Parkinson's. This positions the German market for significant growth, bolstered by contributions from leading companies, advanced research institutions, and supportive government policies.
In terms of market segmentation, the Europe microelectrode array in vitro market is categorized by product type, application, and country. The product types include classical MEA, multiwell-MEA, and CMOS-MEA, with the multiwell-MEA segment holding the largest market share in 2023. In terms of application, the market is divided into cardiomyocytes, nerve, and other categories, with cardiomyocytes also leading in market share.
Key players in the microelectrode array in vitro market include Tucker Davis Technologies, SCREEN Holdings Co., Ltd., Plexon Inc., MaxWell Biosystems AG, Harvard Bioscience Inc., Axion BioSystems Inc., 3Brain AG, NeuroNexus Technologies Inc., MicroElectrodeDevices, Blackrock Microsystems, Inc., NMI Technologietransfer GmbH, and BMSEED. These companies are instrumental in advancing the development and application of microelectrode array technologies in the region.