市场调查报告书
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1283945
鼠标模型市场规模、市场份额、应用分析、区域展望、增长趋势、主要参与者、竞争战略、预测,2023-2031 年Mice Model Market Size, Market Share, Application Analysis, Regional Outlook, Growth Trends, Key Players, Competitive Strategies and Forecasts, 2023 To 2031 |
由于对个性化医疗的需求不断增加、基因研究的进步以及慢性病患病率上升等多种因素,预计未来几年全球小鼠模型市场将出现显着增长。预计。 在 2023-2031 年的预测期内,全球小鼠模型市场规模预计将以 14% 的复合年增长率增长。 小鼠模型广泛用于医学研究,以研究各种疾病和病症,包括癌症、糖尿病和心血管疾病。 这些疾病在全球范围内日益流行,预计将在未来几年推动对小鼠模型的需求。 此外,对个性化医疗的需求不断增加以及对新药和治疗的临床前试验的需求预计将进一步推动市场增长。 此外,新的转基因小鼠模型的开发和基因研究的进步预计将对市场的增长做出重大贡献。 使用小鼠模型研究特定基因的影响及其与环境的相互作用,提高了我们对各种疾病的理解,并促进了新疗法的开发。 总体而言,对个性化医疗的需求不断增长、基因研究的进步以及慢性病患病率的上升预计将在未来几年推动小鼠模型市场的增长。
基因工程小鼠技术的出现是小鼠模型市场的一个里程碑。 这项技术使科学家能够改变小鼠的基因组成,以创建模仿人类遗传疾病的模型。 该技术的进步使小鼠模型成为开发针对多种疾病的新疗法和药物的临床前研究的重要组成部分,对它们的需求猛增。 此外,这项技术还减少了对非人类灵长类动物的研究使用,这具有伦理和财务影响。
癌症、糖尿病和自身免疫性疾病等慢性病患病率的增加是小鼠模型市场的另一个重要驱动力。 小鼠模型被广泛用于研究这些疾病的机制并测试新的治疗方法和药物。 根据美国癌症协会的数据,2020 年美国将有大约 180 万新发癌症病例和大约 60 万癌症死亡病例。 这凸显了对支持癌症研究和药物开发的小鼠模型的高需求。
旨在根据患者的遗传易感性提供适合个体患者的医疗服务的个性化医疗正在蓬勃发展。 小鼠模型在这一领域发挥着重要作用,因为它们使我们能够在临床前研究中检验个性化药物的有效性和安全性。 此外,我们可以通过支持生物标誌物和药物靶点的识别来加速精准医疗的发展。 随着对个性化医疗的需求不断增长,对小鼠模型的需求也有望增加。
在研究中使用动物的限制是小鼠模型市场的主要限制因素。 动物福利问题已经制定了必须遵守的严格规定,以确保符合道德规范的治疗并最大程度地减少痛苦。 这些规定导致成本更高、监管批准时间更长,以及用于研究目的的动物可用性有限。 在某些情况下,完全禁止在研究中使用动物,并且需要替代研究方法,例如计算机建模或细胞培养。 例如,欧盟 (EU) 出台了关于保护用于科学目的的动物的指令 2010/63/EU,强制要求尽可能用非动物替代品代替动物试验。 同样,在美国,《动物福利法》(AWA) 和关于人道关怀和使用实验室动物的公共卫生服务政策规范了动物在研究中的使用。 这些法规增加了替代方法和技术的使用,例如计算机建模、器官芯片和体外分析,这可能会阻碍小鼠模型市场的增长。 然而,儘管存在这些挑战,小鼠模型仍然是研究中有价值的工具,动物福利实践和替代方案的持续创新将有助于克服其中的一些障碍。
小鼠模型市场可按技术细分为 CRISPR/CAS9、显微注射、胚胎干细胞注射、核移植和其他技术。 在这些细分市场中,CRISPR/CAS9 技术细分市场预计将在 2023 年至 2031 年的预测期内以最高的复合年增长率增长。 这得益于CRISPR/CAS9技术在生成基因工程小鼠模型方面的准确性高、效率高等优势。 此外,这项技术使研究人员能够高精度地瞄准和修改特定基因,这对于阐明疾病的遗传基础和开发新疗法至关重要。 按收入计算,显微注射业务将在 2022 年占据最大份额。 这是因为该技术已被广泛应用于生成转基因小鼠模型,用于研究各种人类疾病,如癌症、糖尿病和心血管疾病。 显微注射允许研究人员将外来 DNA 引入小鼠基因组,从而开发出模拟人类疾病的基因工程小鼠模型。
全球小鼠模型市场可以根据药物发现和开发、基础研究和患者来源的异种移植 (PDX) 模型/异种移植等应用进行细分。 其中,药物发现和开发板块将在 2022 年占据最大的市场份额,预计在 2023 年至 2031 年的预测期内将以较大的复合年增长率增长。 对个性化医疗的需求不断增长以及製药公司研发活动的增加是推动这一领域增长的主要因素。 此外,小鼠模型也广泛用于临床前研究,以评估新药的安全性和有效性。 由于政府和私营公司增加对生物医学研究的投资,预计基础研究领域将以显着的复合年增长率增长。 此外,对研究人类疾病及其遗传基础的基因工程小鼠模型的需求不断增加,也促进了这一领域的增长。 预计 PDX 模型/异种移植物在预测期内将适度增长。 这些模型广泛用于癌症研究和药物开发,因为它们模仿了人类肿瘤的生物学行为。
北美在 2022 年占据市场主导地位,占销售额的比例最高。 这是由于先进的医疗保健基础设施的存在、研发投资的增加以及有利的政府举措。 由于多家製药和生物技术公司的存在以及学术实验室对小鼠模型的广泛研究,美国是该地区的一个重要市场。 欧洲的收入仅次于北美,预计在预测期内将出现显着增长,这是由于对个性化医疗的日益关注以及对人性化小鼠模型的需求不断增加。 亚太地区在 2023-2031 年的预测期内增长最快,原因是研发活动投资增加、对药物发现和开发的关注度增加以及研究活动外包给中国和印度等国家的增加。预计创下高复合年增长率。 此外,由于慢性病患病率增加以及政府加大支持研发活动的力度,预计拉丁美洲和中东及非洲地区在预测期内将出现显着增长。
全球鼠标模型市场竞争激烈,参与者众多。 市场上的主要参与者包括 Envigo、Charles River Laboratories International, Inc.、The Jackson Laboratory、Laboratory Corporation of America Holdings (Envigo)、Janvier Labs、Taconic Biosciences, Inc. 和 genOway S.A.,这些公司投资于研发活动和新产品开发,以保持其市场地位。 此外,参与者还注重战略联盟和联合研究以增加市场份额。 例如,2020 年,Charles River Laboratories International, Inc. 与美国国家过敏和传染病研究所 (NIAID) 合作开展了 COVID-19 的临床前研究。 总体而言,市场参与者正专注于各种策略,以保持其市场地位并扩大其在全球鼠标模型市场的影响力。 各种应用对小鼠模型的需求不断增加以及对个性化医疗的需求预计将推动未来几年的市场增长。
The global mice model market is expected to experience significant growth in the coming years, driven by several factors such as increasing demand for personalized medicine, advancements in genetic research, and rising prevalence of chronic diseases. The global mice model market size is expected to grow at a CAGR of 14% during the forecast period of 2023 to 2031. Mice models are widely used in medical research to study various diseases and disorders such as cancer, diabetes, and cardiovascular diseases. The increasing prevalence of these diseases worldwide is expected to drive the demand for mice models in the coming years. Additionally, the growing demand for personalized medicine and the need for preclinical testing of new drugs and therapies are expected to further drive market growth.Furthermore, the development of new genetically modified mice models and the advancements in genetic research are expected to significantly contribute to market growth. The use of mice models in studying the effects of specific genes and their interaction with the environment has provided a better understanding of various diseases and has facilitated the development of new treatments.Overall, the increasing demand for personalized medicine, advancements in genetic research, and rising prevalence of chronic diseases are expected to drive the growth of the mice model market in the coming years.
The advent of genetically modified mice technology has been a game-changer for the Mice Model Market. The technology enables scientists to alter the genetic makeup of mice and create models that mimic human genetic disorders. This advancement has led to a surge in the demand for mice models, as they play a critical role in preclinical research for developing new therapies and drugs for various diseases. Moreover, this technology has also reduced the use of non-human primates in research, which has ethical and financial implications.
The increasing prevalence of chronic diseases such as cancer, diabetes, and autoimmune diseases is another significant driver of the Mice Model Market. Mice models are extensively used to conduct research on the mechanisms of these diseases and test new therapies and drugs. According to the American Cancer Society, there were approximately 1.8 million new cancer cases and 0.6 million cancer deaths in the US in 2020. This highlights the significant demand for mice models to support cancer research and drug development.
There has been a growing trend in personalized medicine, which aims to tailor medical treatment to individual patients based on their genetic makeup. Mice models play a critical role in this field as they enable researchers to study the efficacy and safety of personalized drugs in preclinical trials. Moreover, mice models also facilitate the development of precision medicine by helping researchers to identify biomarkers and potential drug targets. As the demand for personalized medicine continues to increase, the demand for mice models is also expected to rise.
Restrictions on the use of animals in research are a significant restraint in the mice model market. Animal welfare concerns have led to strict regulations that must be followed to ensure ethical treatment and minimize suffering. These regulations have resulted in higher costs, increased time for regulatory approval, and limited availability of animals for research purposes. In some cases, the use of animals in research is completely prohibited, resulting in the need for alternative research methods, such as computer modeling or cell cultures. For instance, the European Union (EU) introduced Directive 2010/63/EU on the protection of animals used for scientific purposes, which mandates that animal experiments must be replaced with non-animal alternatives whenever possible. Similarly, in the United States, the Animal Welfare Act (AWA) and the Public Health Service Policy on Humane Care and Use of Laboratory Animals regulate the use of animals in research. These regulations have led to an increase in the use of alternative methods and technologies, such as in silico modeling, organ-on-a-chip, and in vitro assays, which may hinder the growth of the mice model market. However, despite these challenges, mice models remain a valuable tool in research, and continued innovation in animal welfare practices and alternative methods may help overcome some of these restraints.
The Mice Model Market can be segmented based on technology into CRISPR/CAS9, microinjection, embryonic stem cell injection, nuclear transfer, and other technologies. Among these segments, the CRISPR/CAS9 technology segment is expected to grow at the highest CAGR during the forecast period of 2023 to 2031. This is due to the advantages of the CRISPR/CAS9 technology, such as high precision and efficiency in generating genetically modified mice models. Additionally, this technology enables researchers to target specific genes and modify them with high accuracy, which is crucial for understanding the genetic basis of diseases and developing new treatments.In terms of revenue, the microinjection segment held the largest share in 2022. This is due to the wide application of this technology in generating transgenic mice models for studying a range of human diseases, including cancer, diabetes, and cardiovascular diseases. Microinjection enables researchers to introduce foreign DNA into the mouse genome, resulting in the development of genetically modified mice models that mimic human diseases.
The global mice model market can be segmented based on its applications, which include drug discovery and development, basic research, and patient-derived xenograft (PDX) models/xenografts. Among these, the drug discovery and development segment held the largest market share in terms of revenue in 2022 and is expected to grow at a significant CAGR during the forecast period of 2023 to 2031. The growing demand for personalized medicine and increasing R&D activities by pharmaceutical companies are some of the key factors driving the growth of this segment. Moreover, mice models are widely used for preclinical studies to evaluate the safety and efficacy of new drugs. The basic research segment is also expected to grow at a substantial CAGR owing to the increasing investments by governments and private organizations in biomedical research. Additionally, the rising demand for genetically modified mice models for studying human diseases and their genetic basis is further contributing to the growth of this segment. The PDX models/xenografts segment is expected to witness moderate growth during the forecast period. These models are widely used for cancer research and drug development, as they mimic the biological behavior of human tumors.
North America dominated the market, accounting for the highest revenue percentage in 2022. This is due to the presence of advanced healthcare infrastructure, increased investment in research and development, and favourable government initiatives. The US is the leading market in the region, owing to the presence of several pharmaceutical and biotech companies, along with academic research institutes conducting extensive research on mice models. Europe follows North America in terms of revenue share, and the region is projected to witness significant growth during the forecast period due to increasing focus on personalized medicine and rising demand for humanized mice models. The Asia Pacific region is expected to witness the highest CAGR during the forecast period of 2023 to 2031, due to increasing investment in research and development activities, growing focus on drug discovery and development, and increasing outsourcing of research activities to countries like China and India. Latin America and the Middle East and Africa regions are also projected to witness significant growth during the forecast period due to the growing prevalence of chronic diseases and increasing government initiatives to support research and development activities.
The global mice model market is highly competitive with the presence of various players. Some of the key players operating in the market include Envigo, Charles River Laboratories International, Inc., The Jackson Laboratory, Laboratory Corporation of America Holdings (Envigo), Janvier Labs, Taconic Biosciences, Inc., and genOway S.A. These companies are investing in R&D activities and new product development to maintain their position in the market.In addition, players are also focusing on strategic partnerships and collaborations to expand their market share. For instance, in 2020, Charles River Laboratories International, Inc. partnered with The National Institute of Allergy and Infectious Diseases (NIAID) to conduct preclinical research on COVID-19.Overall, the market players are focusing on various strategies to maintain their market position and expand their presence in the global mice model market. The increasing demand for mice models in various applications and the need for personalized medicine are expected to drive the growth of the market in the coming years.
This study report represents analysis of each segment from 2021 to 2031 considering 2022 as the base year. Compounded Annual Growth Rate (CAGR) for each of the respective segments estimated for the forecast period of 2022 to 2031.
The current report comprises of quantitative market estimations for each micro market for every geographical region and qualitative market analysis such as micro and macro environment analysis, market trends, competitive intelligence, segment analysis, porters five force model, top winning strategies, top investment markets, emerging trends and technological analysis, case studies, strategic conclusions and recommendations and other key market insights.
The complete research study was conducted in three phases, namely: secondary research, primary research, and expert panel review. key data point that enables the estimation of Mice Model market are as follows:
Micro and macro environment factors that are currently influencing the Mice Model market and their expected impact during the forecast period.
Market forecast was performed through proprietary software that analyzes various qualitative and quantitative factors. Growth rate and CAGR were estimated through intensive secondary and primary research. Data triangulation across various data points provides accuracy across various analyzed market segments in the report. Application of both top down and bottom-up approach for validation of market estimation assures logical, methodical and mathematical consistency of the quantitative data.