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市场调查报告书
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1574655

全球癌症抗体药物复合物市场:市场规模、药物批准、价格、销售和临床试验的见解(2030)

Global Cancer Antibody Drug Conjugates Market Size, Drugs Approval, Price, Sales & Clinical Trials Insight 2030

出版日期: | 出版商: KuicK Research | 英文 1300 Pages | 商品交期: 最快1-2个工作天内

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抗体药物复合物(ADC)已成为癌症治疗中的创新治疗剂,它将单株抗体的特异性与细胞毒性药物的功效相结合。这种创新疗法由透过稳定连接体与细胞毒性药物结合的抗体组成,可针对癌细胞,同时最大限度地减少对周围健康组织的损害。抗体药物复合物的快速发展反映了它们在临床和商业上的成功,目前有16个产品在各个市场获得批准,销售额预计将在2023年达到100亿美元,并在2024年首次达到6个月内超过70亿美元。这种成长凸显了抗体药物复合物是更广泛的癌症药物市场中商业上可行的部分,并推动了研究和开发工作,以创造更有效和安全的候选化合物。

截至2024年 10月,全球监管机构已批准 16 种抗体药物复合物,其中 13 种目前可用于临床用于治疗各种癌症类型。其中,代表性的有Padceb、Kadcyla、Enherz等,2023年将占抗体药物复合物总销售额的60%左右。 Enhertu 适用于治疗多种 HER2 阳性实体肿瘤,而 Padcev 和 Kadcyla 仅分别被批准用于治疗膀胱癌和乳癌。这些产品类型显示市场对 ADC 的治疗潜力以及治疗各种癌症类型的有效性越来越有信心。

全球癌症抗体药物复合物市场的特点是竞争格局,针对包括实体肿瘤和血液恶性肿瘤在内的多种癌症的积极发展。然而,其中肺癌目前的开发活动最为广泛,有超过60个候选药物处于临床试验中,包括CAB-AXL-ADC、TQB2102和MYTX-011,其中一个Enhertu已经获得批准。这反映出肺癌治疗的策略转变,肺癌仍然是全球癌症死亡的主要原因之一,并且有很高的未满足的医疗需求。抗体-药物复合物有可能提供更有效、毒性更小的治疗选择,并且在该治疗领域特别有吸引力。

功能 详细资料
关键片段 应用:癌症类型、区域、技术平台
涵盖的适应症 目标疾病:肺癌、乳癌、子宫颈癌、胰臟癌、食道癌等
主要目标国 美国、中国、韩国、加拿大、印度等
目标药 Enhertu、Adcetris、Polivy、Kadcyla 等
报告范围 作用模式、ADC生成、管道和批准的药物见解、销售见解、当前趋势、未来机会、市场驱动因素和挑战
目标公司 Biocytogen、Merck、AstraZeneca、Pfizer、Daiichi Sankyo、ADC Therapeutics等

本报告调查了全球癌症抗体药物复合物市场,并提供了市场概况以及药物趋势、临床试验趋势、区域趋势以及进入市场的公司的竞争格局。

目录

第1章 抗体药物复合物简介

  • 摘要
  • 抗体-药物复合物的作用机制

第2章 抗体药物复合物作为癌症标靶治疗

  • 抗体药物复合物在癌症的应用
  • 抗体-药物复合物的优点
  • 抗体药物复合物与常规治疗的比较

第3章 抗体药物复合物的生成

  • 抗体药物复合物 - Evolution
  • 下一代抗体药物复合物的前景

第4章 依品牌名称、公司和适应症列出的市售已核准抗体药物复合物

第5章 全球癌症抗体药物复合物临床试验概述

  • 依阶段
  • 依适应症
  • 依公司
  • 依患者细分
  • 依国家/地区

第6章 全球癌症抗体药物复合物市场展望

第7章 全球癌症抗体药物复合物的调查和市场趋势(依地区)

  • 美国
  • 中国
  • 欧洲
  • 韩国
  • 澳洲
  • 英国
  • 加拿大
  • 日本
  • 印度
  • 拉丁美洲

第8章 全球癌症抗体药物复合物市场的趋势与发展(按适应症)

  • 肺癌
  • 乳癌
  • 白血病
  • 卵巢癌
  • 胃肠癌
  • 淋巴瘤
  • 泌尿生殖系统癌症
  • 子宫颈癌
  • 头颈癌
  • 脑肿瘤
  • 摄护腺癌
  • 胰臟癌
  • 皮肤癌
  • 食道癌

第9章 癌症抗体药物复合物开发平台,依公司划分

第10章 核准的癌症抗体药物复合物 - 专利、剂量和价格分析

  • Adcetris
  • Kadcyla
  • Besponsa
  • Lumoxiti (Market Withdrawal In 2023)
  • Polivy
  • Padcev
  • Enhertu
  • Trodelvy
  • Blenrep (Partial Market Withdrawal In 2023)
  • Zynlonta
  • Tivdak
  • Elahere
  • Ujvira
  • Akalux
  • Aidixi

第11章 核准的癌症抗体药物复合物 - 到2028年的销售洞察与预测

第12章 依公司、国家、适应症和阶段分析全球癌症抗体药物复合物临床试验的见解

  • 研究
  • 临床前
  • 第一期
  • 第一/二期
  • 第二阶段
  • 第二/第三期
  • 第三期
  • 预登记

第13章 依公司、国家和适应症列出的已上市癌症抗体药物复合物的临床见解

第14章 癌症抗体-药物复合物合併治疗

第15章 全球癌症抗体药物复合物市场概述

第16章 竞争态势

  • Biocytogen
  • Bristol Myers Squibb
  • Eli Lilly
  • Innovent Biologics
  • Merck
  • Pfizer
  • Affinity Biopharma
  • Biokin
  • Synaffix
  • ADC Therapeutics
  • AstraZeneca
  • Daiichi Sankyo
  • Duality Biologics
  • Immunogen
  • LigaChem Biosciences

"Global Cancer Antibody Drug Conjugates Market Size, Drugs Approval, Price, Sales & Clinical Trials Insight 2030" Report Finding and Inclusions:

  • Global Cancer Antibody Drug Conjugates Market: 2020 - 2030
  • Global Cancer Antibody Drug Conjugates Market Opportunity > US$ 50 Billion By 2030
  • Approved Cancer Antibody Drug Conjugates: 16 Drugs
  • Approved Cancer Antibody Drug Conjugates Sales Insights, Patent, Dosage & Price Analysis
  • Cancer Antibody Drug Conjugates In Clinical Trials: > 500 Drugs
  • Cancer Antibody Drug Conjugates Clinical Trials Insight By Company, Country, Indication & Phase
  • Insight On Commercially Approved Antibody Drug Conjugates By Brand Name, Company & Indication
FeaturesDetails
Key Segments:Application by Cancer Type, By Region, Technology Platforms
Indications Covered:Lung Cancer, Breast Cancer, Cervical Cancer, Pancreatic Cancer, Pancreatic Cancer, Esophageal Cancer, among others
Key Countries Covered:US, China, South Korea, Canada, India, among others
Drugs Covered:Enhertu, Adcetris, Polivy, Kadcyla, among others
Report Coverage:Mechanism of Action, ADC Generations, Pipeline & Approved Drugs Insight, Sales Insight, Current Trends, Future Opportunities, Market Drivers & Challenges
Companies Covered:Biocytogen, Merck, AstraZeneca, Pfizer, Daiichi Sankyo, ADC Therapeutics, among others

Antibody drug conjugates (ADCs) have emerged as a transformative class of therapeutics in the cancer treatment landscape, integrating the specificity of monoclonal antibodies with the potency of cytotoxic drugs. These innovative therapies consist of an antibody linked to a cytotoxic agent through a stable linker, allowing targeted delivery to cancer cells while minimizing damage to surrounding healthy tissues. The rapid evolution of antibody drug conjugates reflects their clinical and commercial success, with 16 products currently approved across various markets and sales surpassing US$ 10 Billion in 2023 and US$ 7 Billion in the first 6 months of 2024. This growth highlights antibody drug conjugates as a commercially viable segment of the broader cancer therapeutics market, prompting increased research and development efforts to create more effective and safer candidates.

As of October 2024, regulatory authorities around the world have approved 16 antibody drug conjugates, with 13 currently available for clinical use for different cancer types. Among these, prominent examples include Padcev, Kadcyla, and Enhertu, which collectively accounted for approximately 60% of the total antibody drug conjugates sales in 2023. While Enhertu is indicated for the treatment of several HER2-positive solid cancers, Padcev and Kadcyla are solely approved for the treatment of bladder cancer and breast cancer, respectively. The commercialization of these products demonstrates not only their therapeutic potential but also the market's growing confidence in the effectiveness of ADCs in managing various cancer types.

Global cancer antibody drug conjugates market is characterized by a competitive landscape, with substantial development efforts targeting multiple cancers, including both solid tumors and hematological malignancies. However, out of all these, lung cancer is currently witnessing the most extensive development activity, with over 60 candidates in clinical trials, including CAB-AXL-ADC, TQB2102, and MYTX-011, and one Enhertu, approved for use in clinical setting. This reflects a strategic shift towards addressing the high-unmet medical need in lung cancer, which remains one of the leading causes of cancer mortality worldwide. The potential for antibody drug conjugates to provide more effective and less toxic treatment options makes them particularly attractive in this therapeutic area.

In contrast, however, breast cancer has experienced the highest number of antibody drug conjugates approvals to date, with four approved candidates, contributing significantly to the market's commercial success. Two key players in this domain are the aforementioned Kadcyla and Enhertu, both of which have demonstrated remarkable efficacy and have achieved significant sales milestones. The promising pipeline also includes AstraZeneca and Daiichi Sankyo's Datopotamab Deruxtecan, a TROP2-directed antibody drug conjugate that is currently under review for its use in breast cancer treatment. This continued investment in research and development underscores the critical role antibody drug conjugates play in advancing cancer care.

Regionally, the cancer antibody drug conjugates market is primarily led by the US and China, two of the largest and most dynamic pharmaceutical markets globally. In the US, robust healthcare infrastructure, high R&D expenditure, and a favorable regulatory environment foster innovation and accelerate the approval process for new therapies. Additionally, the presence of major pharmaceutical companies, such as Regeneron, Gilead, Merck and Pfizer, bolsters the competitive landscape, enabling rapid development and commercialization of antibody drug conjugates.

In China, the growing demand for advanced cancer treatments, coupled with increasing government support for biotechnology and pharmaceutical research, has catalyzed significant growth in the antibody drug conjugates sector. Local players like Mabwell, Miracogen, Chia Tai Tianqing Pharmaceutical, Hansoh BioMedical, Sichuan Baili Pharmaceuticals, Biocytogen and Affinity Biopharma are emerging as significant contributors to the market, developing novel Antibody drug conjugates tailored to the specific needs of the Chinese patient population, and out licensing promising candidates to their international counterparts through license agreements.

The global market for cancer antibody drug conjugates represents a dynamic and rapidly evolving segment of the cancer therapeutics landscape. With ongoing clinical trials, innovative research, and increasing regulatory support, antibody drug conjugates are poised to play an increasingly pivotal role in cancer treatment. As efforts continue to address existing challenges and expand the range of approved indications, the future of antibody drug conjugates appears promising, offering hope to patients worldwide in the fight against cancer. The collaborative efforts among pharmaceutical companies, regulatory bodies, and research institutions will be crucial in shaping the next wave of advancements in this exciting therapeutic field.

Table of Contents

1. Introduction To Antibody Drug Conjugates

  • 1.1 Overview
  • 1.2 Mechanism of Antibody Drug Conjugates

2. Antibody Drug Conjugates As Cancer Targeted Therapy

  • 2.1 Applications of Antibody Drug Conjugates in Cancer
  • 2.2 Advantages of Antibody Drug Conjugates
  • 2.3 Comparison of Antibody Drug Conjugates With Traditional Therapies

3. Generations of Antibody Drug Conjugates

  • 3.1 Antibody Drug Conjugates - Evolution
  • 3.2 Next Generation Antibody Drug Conjugates Prospects

4. Commercially Approved Antibody Drug Conjugates By Brand Name, Company & Indication

5. Global Cancer Antibody Drug Conjugates Clinical Trials Overview

  • 5.1 By Phase
  • 5.2 By Indication
  • 5.3 By Company
  • 5.4 By Patient Segment
  • 5.5 By Country

6. Global Cancer Antibody Drug Conjugates Market Outlook

  • 6.1 Current Market Scenario
  • 6.2 Future Growth Avenues

7. Global Cancer Antibody Drug Conjugates Research & Market Trends by Region

  • 7.1 US
  • 7.2 China
  • 7.3 Europe
  • 7.4 South Korea
  • 7.5 Australia
  • 7.6 UK
  • 7.7 Canada
  • 7.8 Japan
  • 7.9 India
  • 7.10 Latin America

8. Global Cancer Antibody Drug Conjugates Market Trends & Development By Indications

  • 8.1 Lung Cancer
  • 8.2 Breast cancer
  • 8.3 Leukemia
  • 8.4 Ovarian Cancer
  • 8.5 Gastrointestinal Cancer
  • 8.6 Lymphoma
  • 8.7 Urogenital Cancer
  • 8.8 Cervical Cancer
  • 8.9 Head & Neck Cancer
  • 8.10 Brain Cancer
  • 8.11 Prostate cancer
  • 8.12 Pancreatic Cancer
  • 8.13 Skin cancer
  • 8.14 Esophageal cancer

9. Cancer Antibody Drug Conjugates Development Platforms By Company

10. Approved Cancer Antibody Drug Conjugates - Patent, Dosage & Price Analysis

  • 10.1 Mylotarg
    • 10.1.1 Availability & Patent Insight
    • 10.1.2 Pricing & Dosage Insight
  • 10.2 Adcetris
    • 10.2.1 Availability & Patent Insight
    • 10.2.2 Pricing & Dosage Insight
  • 10.3 Kadcyla
    • 10.3.1 Availability & Patent Insight
    • 10.3.2 Pricing & Dosage Insight
  • 10.4 Besponsa
    • 10.4.1 Availability & Patent Insight
    • 10.4.2 Pricing & Dosage Insight
  • 10.5 Lumoxiti (Market Withdrawal In 2023)
    • 10.5.1 Availability & Patent Insight
    • 10.5.2 Pricing & Dosage Insight
  • 10.6 Polivy
    • 10.6.1 Availability & Patent Insight
    • 10.6.2 Pricing & Dosage Insight
  • 10.7 Padcev
    • 10.7.1 Availability & Patent Insight
    • 10.7.2 Pricing & Dosage Insight
  • 10.8 Enhertu
    • 10.8.1 Availability & Patent Insight
    • 10.8.2 Pricing & Dosage Insight
  • 10.9 Trodelvy
    • 10.9.1 Availability & Patent Insight
    • 10.9.2 Pricing & Dosage Insight
  • 10.10 Blenrep (Partial Market Withdrawal In 2023)
    • 10.10.1 Availability & Patent Insight
    • 10.10.2 Pricing & Dosage Insight
  • 10.11 Zynlonta
    • 10.11.1 Availability & Patent Insight
    • 10.11.2 Pricing & Dosage Insight
  • 10.12 Tivdak
    • 10.12.1 Availability & Patent Insight
    • 10.12.2 Pricing & Dosage Insight
  • 10.13 Elahere
    • 10.13.1 Availability & Patent Insight
    • 10.13.2 Pricing & Dosage Insight
  • 10.14 Ujvira
    • 10.14.1 Availability & Patent Insight
    • 10.14.2 Pricing & Dosage Insight
  • 10.15 Akalux
    • 10.15.1 Availability & Patent Insight
    • 10.15.2 Pricing & Dosage Insight
  • 10.16 Aidixi
    • 10.16.1 Availability Insight

11. Approved Cancer Antibody Drug Conjugates - Sales Insights & Forecast 2028

  • 11.1 Adcetris
  • 11.2 Padcev
  • 11.3 Tivdak
  • 11.4 Polivy
  • 11.5 Kadcyla
  • 11.6 Besponsa
  • 11.7 Enhertu
  • 11.8 Trodelvy
  • 11.9 Zynlonta
  • 11.10 Elahere
  • 11.11 Blenrep

12. Global Cancer Antibody Drug Conjugates Clinical Trials Insight By Company, Country, Indication & Phase

  • 12.1 Research
  • 12.2 Preclinical
  • 12.3 Phase I
  • 12.4 Phase I/II
  • 12.5 Phase II
  • 12.6 Phase II/III
  • 12.7 Phase III
  • 12.8 Preregistration

13. Marketed Cancer Antibody Drug Conjugates Clinical Insight By Company, Country & Indication

14. Cancer Antibody Drug Conjugates Combination Therapies

15. Global Cancer Antibody Drug Conjugates Market Overview

  • 15.1 Key Market Growth Drivers
  • 15.2 Challenges For Market Growth

16. Competitive Landscape

  • 16.1 Biocytogen
  • 16.2 Bristol Myers Squibb
  • 16.3 Eli Lilly
  • 16.4 Innovent Biologics
  • 16.5 Merck
  • 16.6 Pfizer
  • 16.7 Affinity Biopharma
  • 16.8 Biokin
  • 16.9 Synaffix
  • 16.10 ADC Therapeutics
  • 16.11 AstraZeneca
  • 16.12 Daiichi Sankyo
  • 16.13 Duality Biologics
  • 16.14 Immunogen
  • 16.15 LigaChem Biosciences

List of Figures

  • Figure 1-1: Antibody Drug Conjugates - General Working Mechanism
  • Figure 2-1: Advantages of Antibody Drug Conjugates
  • Figure 3-1: Antibody-Drug Conjugates - Approval by Generation
  • Figure 3-2: Cancer Antibody Drug Conjugates - Opportunities for Next-Generation Development
  • Figure 5-1: Global - Cancer Antibody Drug Conjugates In Clinical Trials By Phase, 2024 Till 2030
  • Figure 5-2: Global- Cancer Antibody Drug Conjugates In Clinical Trials By Indication, 2024 Till 2030
  • Figure 5-3: Global - Cancer Antibody Drug Conjugates In Clinical Trials By Company, 2024 Till 2030
  • Figure 5-4: Global - Cancer Antibody Drug Conjugates In Clinical Trials By Patient Segment, 2024 Till 2030
  • Figure 5-5: Global - Cancer Antibody Drug Conjugates In Clinical Pipeline By Country, 2024 Till 2030
  • Figure 6-1: Global - Cancer Antibody Drug Conjugates Market (US$ Million), 2020-2024
  • Figure 6-2: Global -Cancer Antibody Drug Conjugates Sales by Drug (US$ Million), Q1'2024
  • Figure 6-3: Global - Cancer Antibody Drug Conjugates Sales by Drug (US$ Million), Q2'2024
  • Figure 6-4: Global - Cancer Antibody Drug Conjugates Sales by Drug (US$ Million), H1'2024
  • Figure 6-5: Global - Cancer Antibody Drug Conjugates Market Share by Drugs (%), H1'2024
  • Figure 6-6: Global - Cancer Antibody Drug Conjugates Market (US$ Million), Q1 & Q2'2024
  • Figure 6-7: Global - Cancer Antibody Drug Conjugates Market by Drug (US$ Million), 2023
  • Figure 6-8: Global - Cancer Antibody Drug Conjugates Market Share by Drugs (%), 2023
  • Figure 6-9: Global - Cancer Antibody Drug Conjugates Market (US$ Million), Q1-Q4'2023
  • Figure 6-10: Global - Cancer Antibody Drug Conjugates Market Forecast (US$ Billion), 2024 - 2030
  • Figure 7-1: Daiichi Sankyo DXd ADC Technology - Clinical Candidates
  • Figure 7-2: India - Branded v/s Biosimilar Trastuzumab Emtansine Price by Supply (US$), October'2024
  • Figure 8-1: Datopotamab Deruxtecan Phase 3 (NCT04656652) Study - Initiation & Completion Year
  • Figure 8-2: Luveltamab tazevibulin Phase 2 (NCT06555263) Study - Initiation & Completion Year
  • Figure 8-3: Ifinatamab Deruxtecan Phase 3 (NCT06203210) Study - Initiation & Completion Year
  • Figure 8-4: Sigvotatug Vedotin Phase 3 (NCT06012435) Study - Initiation & Completion Year
  • Figure 8-5: Sacituzumab Tirumotecan Phase 3 (NCT06074588) Study - Initiation & Completion Year
  • Figure 8-6: Datopotamab deruxtecan Phase 3 (NCT05104866) Study - Initiation & Completion Year
  • Figure 8-7: Datopotamab deruxtecan Phase 3 (NCT06112379) Study - Initiation & Completion Year
  • Figure 8-8: TQB2102 Phase 3 (NCT06561607) Study - Initiation & Completion Year
  • Figure 8-9: ORM-5029 Phase 1 (NCT05511844) Study - Initiation & Completion Year
  • Figure 8-10: BMS-986497 Phase 1 (NCT06419634) Study - Initiation & Completion Year
  • Figure 8-11: JBH492 Phase 1 (NCT04240704) Study - Initiation & Completion Year
  • Figure 8-12: Rinatabart sesutecan Phase 3 (NCT06619236) Study - Initiation & Completion Year
  • Figure 8-13: Luveltamab tazevibulin Phase 2/3 (NCT05870748) Study - Initiation & Completion Year
  • Figure 8-14: Raludotatug Deruxtecan (R-DXd) Phase 2/3 (NCT06161025) Study - Initiation & Completion Year
  • Figure 8-15: AZD5335 Phase 1/2 (NCT05797168) Study - Initiation & Completion Year
  • Figure 8-16: Dato-DXd Phase 2 (NCT05489211) Study - Initiation & Completion Year
  • Figure 8-17: IKS014 Phase 1 (NCT05872295) Study - Initiation & Completion Year
  • Figure 8-18: AZD0901 Phase 2 (NCT06219941) Study - Initiation & Completion Year
  • Figure 8-19: Polatuzumab Vedotin Phase 2 (NCT05410418) Study - Initiation & Completion Year
  • Figure 8-20: Loncastuximab tesirine Phase 2 (NCT05453396) Study - Initiation & Completion Year
  • Figure 8-21: Blenrep Phase 2 (NCT04676360) Study - Initiation & Completion Year
  • Figure 8-22: Zilovertamab vedotin Phase 1/2 (NCT06395103) Study - Initiation & Completion Year
  • Figure 8-23: Padcev Phase 2 (NCT05775471) Study - Initiation & Completion Year
  • Figure 8-24: Trodelvy Phase 2 (NCT05581589) Study - Initiation & Completion Year
  • Figure 8-25: BL-B01D1 Phase 2 (NCT05785039) Study - Initiation & Completion Year
  • Figure 8-26: 9MW2821 Phase 3 (NCT06196736) Study - Initiation & Completion Year
  • Figure 8-27: Trodelvy Phase 2 (NCT05838521) Study - Initiation & Completion Year
  • Figure 8-28: Enhertu Phase 2 (NCT04482309) Study - Initiation & Completion Year
  • Figure 8-29: 9MW2821 Phase 1/2 (NCT05216965) Study - Initiation & Completion Year
  • Figure 8-30: Aidixi Phase 2 (NCT06003231) Study - Initiation & Completion Year
  • Figure 8-31: Padcev Phase 2 (NCT04225117) Study - Initiation & Completion Year
  • Figure 8-32: Ozuriftamab vedotin Phase 1/2 (NCT03504488) Study - Initiation & Completion Year
  • Figure 8-33: Panitumumab-IRDye800 Phase 1/2 (NCT03510208) Study - Initiation & Completion Year
  • Figure 8-34: Patritumab deruxtecan (HER3-DXd) Phase 2 (NCT05865990) Study - Initiation & Completion Year
  • Figure 8-35: Trodelvy Phase 2 (NCT03725761) Study - Initiation & Completion Year
  • Figure 8-36: HS-20093 Phase 2 (NCT06001255) Study - Initiation & Completion Year
  • Figure 8-37: FOR46 Phase 1b/2 (NCT05011188) Study - Initiation & Completion Year
  • Figure 8-38: ARX517 Phase 1 (NCT04662580) Study - Initiation & Completion Year
  • Figure 8-39: Pancreatic Ductal Adenocarcinoma - Prevalence Compared to Other Pancreatic Cancer Types
  • Figure 8-40: SOT102 Phase 1/2 (NCT05525286) Study - Initiation & Completion Year
  • Figure 8-41: TORL-2-307 Phase 1 (NCT05156866) Study - Initiation & Completion Year
  • Figure 8-42: EBC-129 Phase 1 (NCT05701527) Study - Initiation & Completion Year
  • Figure 8-43: Panitumumab-IRDye800 Phase 1/2 (NCT03384238) Study - Initiation & Completion Year
  • Figure 8-44: Ozuriftamab vedotin Phase 1/2 (NCT03504488) Study - Initiation & Completion Year
  • Figure 8-45: Vobramitamab duocarmazine (MGC018) Phase 1 (NCT05293496) Study - Initiation & Completion Year
  • Figure 8-46: AMT253 Phase 1/2 (NCT06209580) Study - Initiation & Completion Year
  • Figure 8-47: Zirconium Zr 89 Crefmirlimab Berdoxam Phase 2 (NCT05013099) Study - Initiation & Completion Year
  • Figure 8-48: Enhertu Phase 2 (NCT05480384) Study - Initiation & Completion Year
  • Figure 8-49: HS-20093 Phase 2 (NCT06112704) Study - Initiation & Completion Year
  • Figure 8-50: DP303c Phase 1/2 (NCT06577376) Study - Initiation & Completion Year
  • Figure 9-1: Proprietary ADC Technology - Seagen
  • Figure 9-2: ALE.P02 & ALE.P03 - Alentis Therapeutics
  • Figure 9-3: TRAAC- Tallac Therapeutics
  • Figure 9-4: ATAC- Heidelberg Pharma
  • Figure 9-5: Tub-tag(R) & P5 - Tubulis
  • Figure 10-1: Mylotarg - FDA Approval, Withdrawal & Re-Approval Year
  • Figure 10-2: Mylotarg - Approval Year by Region
  • Figure 10-3: Mylotarg - Cost of 4.5 mg Supply in US (US$), October'2024
  • Figure 10-4: Mylotarg - Cost of 5 mg Supply in UK (US$), October'2024
  • Figure 10-5: US - Adcetris FDA Approval Year by Indication
  • Figure 10-6: Adcetris - Approval Year by Region
  • Figure 10-7: Japan - Adcetris PMDA Approval Year by Indication
  • Figure 10-8: US - Adcetris Orphan Drug Designation Approval Year by Indication
  • Figure 10-9: Adcetris - Patent Expiration by Region
  • Figure 10-10: Adcetris - Cost of 50 mg Supply in US & UK (US$), October'2024
  • Figure 10-11: US - Kadcyla FDA Approval Year by Indication
  • Figure 10-12: Kadcyla - Approval Year by Region
  • Figure 10-13: US - Kadcyla FDA Approval & Patent Expiration Year
  • Figure 10-14: Kadcyla - Cost of Supply in US, Europe & UK (US$), October'2024
  • Figure 10-15: Kadcyla - Recommended Dose after 1st & 2nd Dose Reduction (mg/kg)
  • Figure 10-16: Besponsa - Approval Year by Region
  • Figure 10-17: Besponsa - Cost of 0.9 mg Supply in US, October'2024
  • Figure 10-18: Besponsa - Cost of 1 mg Supply in Europe & UK (US$), October'2024
  • Figure 10-19: Lumoxiti - Orphan Designation Years
  • Figure 10-20: Lumoxiti - Patent Expiry Years
  • Figure 10-21: Lumoxiti - Cost of 1 mg Supply in US & Europe (US$), October'2024
  • Figure 10-22: Polivy - Approval Year by Region
  • Figure 10-23: Polivy - Orphan Drug Designation Approval Year by Region
  • Figure 10-24: US - Polivy Orphan Drug Designation Approval & Exclusivity Year
  • Figure 10-25: Polivy - Cost of 140 mg Supply in Europe (US$), October'2024
  • Figure 10-26: Polivy - Cost of 30 & 140 mg Supply in US & UK (US$), October'2024
  • Figure 10-27: Padcev - Approval Year by Region
  • Figure 10-28: US - Padcev FDA Approval & Patent Expiration Year
  • Figure 10-29: Padcev - Cost of 20 & 30 mg Supply In US & Europe (US$), October'2024
  • Figure 10-30: Enhertu - Approval Year by Region
  • Figure 10-31: US - Polivy FDA Approval Year by Indication
  • Figure 10-32: Enhertu - FDA Orphan Drug Designation & Exclusivity Expiration Year
  • Figure 10-33: Enhertu - Cost of 100 mg Supply In US, Europe & UK (US$), October'2024
  • Figure 10-34: US - Trodelvy FDA Approval by Indication
  • Figure 10-35: Trodelvy - Approval Year by Region
  • Figure 10-36: Trodelvy - Patent Expiration by Region
  • Figure 10-37: Trodelvy - Cost of 180 mg Supply In US & UK (US$), October'2024
  • Figure 10-38: Trodelvy - Cost of 180 & 200 mg Supply In Europe (US$), October'2024
  • Figure 10-39: Blenrep - FDA & EMA Orphan Drug Designations
  • Figure 10-40: Blenrep - FDA & EMA Approval
  • Figure 10-41: Zynlonta - FDA & EMA Approval Years
  • Figure 10-42: Zynlonta - FDA & EMA Orphan Drug Designation Years
  • Figure 10-43: Zynlonta - Cost of 10 mg Supply In US, Europe & UK (US$), October'2024
  • Figure 10-44: Tivdak - Cost of 40 mg Supply In US & Europe (US$), October'2024
  • Figure 10-45: Elahere - Cost of Unit & Supply In US (US$), October'2024
  • Figure 10-46: Ujvira - Cost of 100 mg & 160 mg Supply (US$), October'2024
  • Figure 10-47: Akalux - Sakigake Designation & PMDA Approval Year
  • Figure 10-48: Aidixi - China Approval Year & FDA Breakthrough Therapy Designation Year
  • Figure 11-1: Adcetris - Global Annual Sales (US$ Million), 2020-2024
  • Figure 11-2: Adcetris - Global Quarterly Sales (US$ Million), Q1 & Q2'2024
  • Figure 11-3: Adcetris - Global Quarterly Sales (US$ Million), Q1-Q4'2023
  • Figure 11-4: Padcev - Global Annual Sales (US$ Million), 2020-2024
  • Figure 11-5: Padcev - Global Quarterly Sales (US$ Million), Q1 & Q2'2024
  • Figure 11-6: Padcev - Global Quarterly Sales (US$ Million), Q1-Q4'2023
  • Figure 11-7: Tivdak - Global Annual Sales (US$ Million), 2021-2024
  • Figure 11-8: Tivdak - Global Quarterly Sales (US$ Million), Q1 & Q2'2024
  • Figure 11-9: Tivdak - Global Quarterly Sales (US$ Million), Q1-Q4'2023
  • Figure 11-10: Polivy - Global Sales Values (US$ Million), 2020-2024
  • Figure 11-11: Polivy - Global Quarterly Sales Values (US$ Million), Q1 & Q2'2024
  • Figure 11-12: Polivy - Global Sales By Region (%), H1'2024
  • Figure 11-13: Polivy - US Annual Sales Values (US$ Million), 2020-2024
  • Figure 11-14: Polivy - US Quarterly Sales Values (US$ Million), Q1 & Q2'2024
  • Figure 11-15: Polivy - Europe Annual Sales Values (US$ Million), 2020-2024
  • Figure 11-16: Polivy - Europe Quarterly Sales Values (US$ Million), Q1 & Q2'2024
  • Figure 11-17: Polivy - Japan Annual Sales Values (US$ Million), 2020-2024
  • Figure 11-18: Polivy - Global Sales By Region (US$ Million), Q1-Q4'2023
  • Figure 11-19: Polivy - Global Sales By Region (%), 2023
  • Figure 11-20: Polivy - Global Quarterly Sales Values (US$ Million), Q1-Q4'2023
  • Figure 11-21: Polivy - US Quarterly Sales Values (US$ Million), Q1-Q4'2023
  • Figure 11-22: Polivy - Europe Quarterly Sales Values (US$ Million), Q1-Q4'2023
  • Figure 11-23: Polivy - Japan Quarterly Sales Values (US$ Million), Q1-Q4'2023
  • Figure 11-24: Polivy - ROW Quarterly Sales Values (US$ Million), Q1-Q4'2023
  • Figure 11-25: Kadcyla - Global Sales Values (US$ Million), 2020-2024
  • Figure 11-26: Kadcyla - Global Quarterly Sales Values (US$ Million), Q1 & Q2'2024
  • Figure 11-27: Kadcyla - Global Sales By Region (%), H1'2024
  • Figure 11-28: Kadcyla - Global Quarterly Sales Values (US$ Million), Q1-Q4'2023
  • Figure 11-29: Kadcyla - Global Sales By Region (US$ Million), Q1-Q4'2023
  • Figure 11-30: Kadcyla - Global Sales By Region (%), 2023
  • Figure 11-31: Kadcyla - US Annual Sales Values (US$ Million), 2020-2024
  • Figure 11-32: Kadcyla - US Quarterly Sales Values (US$ Million), Q1 & Q2'2024
  • Figure 11-33: Kadcyla - US Quarterly Sales Values (US$ Million), Q1-Q4'2023
  • Figure 11-34: Kadcyla - Europe Annual Sales Values (US$ Million), 2020-2024
  • Figure 11-35: Kadcyla - Europe Quarterly Sales Values (US$ Million), Q1 & Q2'2024
  • Figure 11-36: Kadcyla - Europe Quarterly Sales Values (US$ Million), Q1-Q4'2023
  • Figure 11-37: Kadcyla - Japan Annual Sales Values (US$ Million), 2020-2024
  • Figure 11-38: Kadcyla - Japan Quarterly Sales Values (US$ Million), Q1 & Q2'2024
  • Figure 11-39: Kadcyla - Japan Quarterly Sales Values (US$ Million), Q1-Q4'2023
  • Figure 11-40: Kadcyla - ROW Annual Sales Values (US$ Million), 2020-2024
  • Figure 11-41: Kadcyla - ROW Quarterly Sales Values (US$ Million), Q1 & Q2'2024
  • Figure 11-42: Kadcyla - ROW Quarterly Sales Values (US$ Million), Q1-Q4'2023
  • Figure 11-43: Besponsa - Global Annual Sales (US$ Million), 2020-2023
  • Figure 11-44: Besponsa - Global Sales by Region (US$ Million), 2023
  • Figure 11-45: Besponsa - Quarterly Sales by Region (%), 2023
  • Figure 11-46: Besponsa - Global Quarterly Sales (US$ Million), Q1-Q4'2023
  • Figure 11-47: Besponsa - US Annual Sales (US$ Million), 2020-2023
  • Figure 11-48: Besponsa - Europe Quarterly Sales (US$ Million), 2022
  • Figure 11-49: Besponsa - ROW Quarterly Sales (US$ Million), 2022
  • Figure 11-50: Enhertu - Global Annual Sales (US$ Million), 2020-2024
  • Figure 11-51: Enhertu - Global Quarterly Sales Values (US$ Million), Q1 & Q2'2024
  • Figure 11-52: Enhertu - Global Quarterly Sales (US$ Million), 2022
  • Figure 11-53: Trodelvy - Global Annual Sales (US$ Million), 2020-2024
  • Figure 11-54: Trodelvy - Global Quarterly Sales (US$ Million), Q1 & Q2'2024
  • Figure 11-55: Trodelvy - Global Quarterly Sales (US$ Million), Q1-Q4'2023
  • Figure 11-56: Trodelvy - Annual Sales By Region (US$ Million), 2023
  • Figure 11-57: Trodelvy - Annual Sales By Region (%), 2023
  • Figure 11-58: Trodelvy - US Annual Sales (US$ Million), 2020-2024
  • Figure 11-59: Trodelvy - US Quarterly Sales (US$ Million), Q1 & Q2'2024
  • Figure 11-60: Trodelvy - US Quarterly Sales (US$ Million), Q1-Q4'2023
  • Figure 11-61: Trodelvy - Europe Annual Sales (US$ Million), 2020-2024
  • Figure 11-62: Trodelvy - Europe Quarterly Sales (US$ Million), Q1 & Q2'2024
  • Figure 11-63: Trodelvy - Europe Quarterly Sales (US$ Million), Q1-Q4'2023
  • Figure 11-64: Trodelvy - ROW Annual Sales (US$ Million), 2020-2024
  • Figure 11-65: Trodelvy - ROW Quarterly Sales (US$ Million), Q1 & Q2'2024
  • Figure 11-66: Trodelvy - ROW Quarterly Sales (US$ Million), Q1-Q4'2023
  • Figure 11-67: Zynlonta - Global Annual Sales (US$ Million), 2021-2024
  • Figure 11-68: Zynlonta - Global Quarterly Sales (US$ Million), Q1 & Q2'2024
  • Figure 11-69: Zynlonta - Global Quarterly Sales (US$ Million), Q1-Q4'2023
  • Figure 11-70: Elahere - Global Annual Sales (US$ Million), 2022-2024
  • Figure 11-71: Elahere - Global Quarterly Sales (US$ Million), Q1 & Q2'2024
  • Figure 11-72: Elahere - Global Quarterly Sales (US$ Million), Q1-Q4'2023
  • Figure 11-73: Blenrep - Global Annual Sales (US$ Million), 2020-2023
  • Figure 11-74: Blenrep - Europe Quarterly Sales Value (US$ Million), Q1-Q4'2023
  • Figure 14-1: Antibody Drug Conjugate Combinations in Studies
  • Figure 14-2: Approved Antibody Drug Conjugate Combinations

List of Tables

  • Table 3-1: First Generation Antibody Drug Conjugates - Examples
  • Table 3-2: Second Generation Antibody Drug Conjugates - Examples
  • Table 3-3: Third Generation Antibody Drug Conjugates - Examples
  • Table 3-4: Fourth Generation Antibody Drug Conjugates - Examples
  • Table 4-1: Approved Antibody Drug Conjugates
  • Table 6-1: Cancer Antibody Drug Conjugates Market - Recent Acquisition Deals
  • Table 6-2: Cancer Antibody Drug Conjugates - Recent Collaborations
  • Table 6-3: Cancer Antibody Drug Conjugates - Companies Securing Funding for Clinical Development
  • Table 6-4: Cancer Antibody Drug Conjugates - Companies Announcing Plans for Manufacturing Facilities
  • Table 6-5: Cancer Antibody Drug Conjugates - Recent Regulatory Designations
  • Table 6-6: Cancer Antibody Drug Conjugates - Recent IND Clearances
  • Table 7-1: US - Approved Cancer Antibody Drug Conjugates, October'2024
  • Table 7-2: US - Antibody Drug Conjugate Under FDA Review, October'2024
  • Table 7-3: China - Approved Antibody Drug Conjugates, October'2024
  • Table 7-4: EU - Approved Cancer Antibody Drug Conjugates, October'2024
  • Table 7-5: Australia - Approved Cancer Antibody Drug Conjugates, October'2024
  • Table 7-6: Canada - Approved Cancer Antibody Drug Conjugates, October'2024
  • Table 7-7: Japan - Approved Cancer Antibody Drug Conjugates, October'2024
  • Table 8-1: Lung Cancer - Approved Antibody Drug Conjugates
  • Table 8-2: Breast Cancer - Approved Antibody Drug Conjugates
  • Table 8-3: Leukemia - Approved Antibody Drug Conjugates
  • Table 8-4: Ovarian Cancer - Approved Antibody Drug Conjugate
  • Table 8-5: Gastrointestinal Cancer - Approved Antibody Drug Conjugates
  • Table 8-6: Lymphoma - Approved Antibody Drug Conjugates
  • Table 8-7: Urogenital Cancer - Approved Antibody Drug Conjugates
  • Table 8-8: Cervical Cancer - Approved Antibody Drug Conjugates
  • Table 8-9: Head & Neck Cancer - Approved Antibody Drug Conjugates
  • Table 10-1: Adcetris - Recommended Dosage
  • Table 14-1: Antibody Drug Conjugate Combinations - Ongoing Clinical Trials