市场调查报告书
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CAR-T细胞疗法市场,规模,占有率,趋势,产业分析报告:各适应症,标的抗原,各地区 - 市场预测,2025年~2034年CAR-T Cell Therapy Market Size, Share, Trends, Industry Analysis Report: By Indication, Target Antigen, and Region (North America, Europe, Asia Pacific, Latin America, and Middle East & Africa) - Market Forecast, 2025-2034 |
根据 Polaris Market Research 的最新研究,预计到 2034 年,全球 CAR-T 细胞治疗市场规模将达到 1888.4 亿美元。该报告提供了对当前市场动态的详细洞察,并对未来市场成长进行了分析。
嵌合抗原受体 T 细胞 (CAR-T) 疗法代表了癌症治疗的进步,并彻底改变了免疫肿瘤学。这种治疗是个人化的,透过改造患者的 T 细胞来表达针对特定癌症抗原的合成受体,对特定癌症(特别是血液系统恶性肿瘤)非常有效,从而提供了广泛的治疗选择。在生物技术的快速进步、CAR-T疗法批准率的提高以及对创新癌症治疗的需求不断增长的推动下,全球CAR-T细胞疗法市场在过去十年中经历了快速增长。
全球癌症发生率不断上升,以及对精准医疗的日益青睐,推动了对 CAR-T 细胞疗法等先进疗法的需求。此外,支持性监管框架和加速审批途径正在加速 CAR-T 疗法的上市。政府和私人研究投资正在进一步推动CAR-T细胞治疗市场的扩张。
下一代 CAR-T 疗法(包括多标靶 CAR-T 细胞和装甲 CAR-T 细胞)的发展正在推动 CAR-T 细胞疗法市场的成长。多标靶 CAR-T 细胞旨在识别多种抗原,解决肿瘤异质性和抗原逃脱等限制传统 CAR-T 治疗有效性的问题。武装CAR-T细胞旨在透过分泌细胞激素和其他分子来克服免疫抑制的肿瘤微环境,从而增强抗肿瘤活性。
CAR-T 疗法的应用正在扩展到肿瘤学之外。研究人员正在探索其治疗狼疮和多发性硬化症等自体免疫疾病以及爱滋病毒等传染病的潜力。这些新应用预计将显着扩大市场范围和影响力。
有迹象表明,滤泡性淋巴瘤 (FL) 领域预计将以最快的速度增长,在预测期内复合年增长率为 43.2%。
基于标靶抗原,CD19/CD22抗原片段在瀰漫性大B细胞淋巴瘤(DLBCL)和急性淋巴性白血病(ALL)等B细胞恶性肿瘤的治疗中具有明确的作用并受到重视。达到62585亿美元,占最大市场占有率。
在全球市场中,2024年北美CAR-T细胞治疗市场占47.16%的市占率。这是由于先进的医疗基础设施、高研发投资和血液恶性肿瘤的高盛行率。
由于復发性或难治性血癌盛行率上升以及人们越来越关注扩大先进治疗的可及性,欧洲CAR-T 细胞治疗市场将在预测期内增长,预计复合年增长率为33.2 %。
作为全球主要市场企业的一个例子,Bluebird Bio,Celgene Corporation,Gilead Sciences,Cellectis,Servier Laboratories,Pfizer Inc.,Merck,Amgen,Intellia Therapeutics,Novartis,Caribou Biosciences,Celyad,Bellicum Pharmaceuticals,Noile-Immune Biotech,南京市 Legend Biotechnology Co.等能举出(举行)。
The global CAR-T cell therapy market size is expected to reach USD 188.84 billion by 2034, according to a new study by Polaris Market Research. The report "CAR-T Cell Therapy Market Size, Share, Trends, Industry Analysis Report: By Indication, Target Antigen [CD19/CD22, BCMA (B-Cell Maturation Antigen), and Others], and Region (North America, Europe, Asia Pacific, Latin America, and Middle East & Africa) - Market Forecast, 2025-2034" gives a detailed insight into current market dynamics and provides analysis on future market growth.
Chimeric Antigen Receptor T-cell (CAR-T) therapy represents an advancement in cancer treatment, transforming immuno-oncology. The therapy offers personalized and highly effective treatment options for certain cancers, particularly hematological malignancies, by engineering a patient's T-cells to express synthetic receptors that target specific cancer antigens. The global CAR-T cell therapy market has witnessed exponential growth over the last decade, driven by rapid advancements in biotechnology, increasing approval rates of CAR-T therapies, and rising demand for innovative cancer treatments.
The increasing prevalence of cancer globally, coupled with a growing preference for precision medicine, has fueled demand for advanced treatment modalities such as CAR-T cell therapy. Moreover, supportive regulatory frameworks and rapid approval pathways have accelerated the availability of CAR-T therapies. Government and private investments in research further propel the CAR-T cell therapy market expansion.
The development of next-generation CAR-T therapies, including multi-target CAR-T cells and armored CAR-T cells, is driving the CAR-T cell therapy market growth. Multi-target CAR-T cells are engineered to recognize multiple antigens, addressing issues such as tumor heterogeneity and antigen escape, which limit the efficacy of traditional CAR-T treatments. Armored CAR-T cells are designed to overcome the immunosuppressive tumor microenvironment by secreting cytokines or other molecules to enhance anti-tumor activity.
The application of CAR-T therapy is expanding beyond oncology. Researchers are exploring its potential in treating autoimmune diseases such as lupus and multiple sclerosis and infectious diseases, including HIV. These novel applications are estimated to significantly broaden the market scope and impact.
In terms of indication, the follicular lymphoma (FL) segment is expected to grow at the fastest pace, with a CAGR of 43.2% during the forecast period due to the rising incidence of refractory and high-risk cancer cases.
Based on target antigen, the CD19/CD22 antigen segment, valued at USD 6,258.5 billion in 2024, held the largest market share owing to its established role in treating B-cell malignancies such as diffuse large B-cell lymphoma (DLBCL) and acute lymphoblastic leukemia (ALL).
In the global market, the North America CAR-T cell therapy market held a 47.16% market share in 2024 due to the presence of advanced healthcare infrastructure, significant research and development investments, and a high prevalence of hematologic malignancies.
The Europe CAR-T cell therapy market is expected to witness a CAGR of 33.2% during the forecast period due to increased focus on expanding access to advanced therapies, coupled with the rising prevalence of relapsed or refractory hematologic cancers.
A few of the global key market players are Bluebird Bio; Celgene Corporation; Gilead Sciences; Cellectis; Servier Laboratories; Pfizer Inc.; Merck; Amgen; Intellia Therapeutics; Novartis; Caribou Biosciences; Celyad; Bellicum Pharmaceuticals, Inc.; Noile-Immune Biotech; Nanjing Legend Biotechnology Co., Ltd.; Johnson & Johnson; and Sangamo Therapeutics, Inc.
Polaris Market Research has segmented the CAR-T cell therapy market report on the basis of indication, antigen, and region:
Chapter 1. Introduction
Chapter 2. Executive Summary
Chapter 3. Research Methodology
Chapter 4. CAR-T Cell Therapy Market Insights
Chapter 5. CAR-T Cell Therapy Market Assessment by Indication
Chapter 6. Global CAR-T Cell Therapy Market, by Target Antigen
Chapter 7. CAR-T Cell Therapy Market Assessment by Geography
Chapter 8. Competitive Landscape
Chapter 9. Company Profiles
Table 1 Selected significant catalysts in CAR-T
Table 2 Various antigen targets are investigated for solid tumors
Table 3 Top Developers in CAR T cell clinical trials (September 2019)
Table 4 Catalyst for Small Players
Table 5 Selected deals and partnerships
Table 6 Cost of production (Lentivirus), 2022, (USD Billion)
Table 7 Cost of production (Plasmid), 2022, (USD Billion)
Table 8 Reimbursement amounts for CAR-T therapies per region, 2022, (USD Billion)
Table 9 Global CAR-T Cell Therapy Market, by Indication, 2020-2034, (USD Billion)
Table 10 Global CAR-T Cell Therapy Market, by DLBCL, 2020-2034, (USD Billion)
Table 11 Global CAR-T Cell Therapy Market, by ALL, 2020-2034, (USD Billion)
Table 12 Global CAR-T Cell Therapy Market, by CLL, 2020-2034, (USD Billion)
Table 13 Global CAR-T Cell Therapy Market, by MM, 2020-2034, (USD Billion)
Table 14 Global CAR-T Cell Therapy Market, by FL, 2020-2034, (USD Billion)
Table 15 Global CAR-T Cell Therapy Market, by Mastozytosis, 2020-2034, (USD Billion)
Table 16 Global CAR-T Cell Therapy Market, by Myeloid Fibrosis, 2020-2034, (USD Billion)
Table 17 Global CAR-T Cell Therapy Market, by MLL, 2020-2034, (USD Billion)
Table 18 Global CAR-T Cell Therapy Market, by Thymic Cancer, 2020-2034, (USD Billion)
Table 19 Global CAR-T Cell Therapy Market, by Glioblastoma, 2020-2034, (USD Billion)
Table 20 Global CAR-T Cell Therapy Market, by AML, 2020-2034, (USD Billion)
Table 21 Global CAR-T Cell Therapy Market, by Other Indications, 2020-2034, (USD Billion)