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3D 细胞培养市场:按产品、应用、最终用户分类:2021-2031 年全球机遇分析和行业预测3D Cell Culture Market By Product, By Application, By End User : Global Opportunity Analysis and Industry Forecast, 2021-2031 |
3D 细胞培养是一种体外技术,可让细胞在人工创造的环境中生长。
这些环境与本地组织的结构和功能非常相似。 3D 细胞培养技术通过与类似于体内的三维环境相互作用,帮助刺激细胞分化、增殖和迁移。 由于 3D 细胞培养可以模拟体内组织的结构、活动和微环境,因此该技术在药物筛选、再生医学、干细胞治疗、癌症研究和细胞生物学方面具有许多潜在应用。 在 3D 培养中,细胞外基质分泌细胞因子和营养因子,并进行直接接触以实现细胞间通讯,类似于体内环境。 二维环境中这些因素的变化会深刻影响细胞间的通讯,导致细胞形态和增殖发生改变。 这种技术在医疗保健研究领域越来越受欢迎,因为 2D 培养物无法再现 3D 培养物的结构和復杂细胞基质。 此外,3D 细胞培养可以提高效率并降低整个研发过程的成本。
3D 细胞培养市场按产品细分为基于支架的平台、无支架平台、凝胶、生物反应器、微芯片和服务。 基于支架的平台用于通过提供一个表面来修改细胞培养程序,细胞可以在该表面上轻鬆地进行 3D 生长。 支架用于药物发现和细胞生长,因为它们有多种材料和结构可供选择。 支架也很容易成像,并具有简单化验协议的优势。 此外,支架的机械和生化特性可以根据应用需要轻鬆修改。 因此,由于对用于创建 3D 细胞培养的基于脚手架的平台的高需求,预计该细分市场将在整个预测期内主导产品细分市场。 然而,基于支架的平台可以通过吸附测试物质、限制下游端点进行分析以及允许引入不同的生物物质来抑製片段生长。
根据应用,3D 细胞培养市场分为癌症研究、干细胞研究、药物发现和再生医学。 癌症研究领域预计将成为分析期内增长最大的领域。 这包括促进细胞生长和改变形态,揭示真实的药物反应,捕捉表型异质性,以及实现基因表达和细胞行为的实验操作。,以代表肿瘤微环境。 利用 3D 细胞培养优势的早期临床前研究可以决定性地提高我们对癌症生物学的理解。 这包括消除较差的候选药物和识别以前在二维培养中无法获得的生理学相关目标。 这可能会显着促进该细分市场的增长。
根据最终用户,全球 3D 细胞培养市场分为生物技术和製药公司、合同研究机构和学术机构。 在整个分析期间,学术机构部门在最终用户领域占据主导地位。 由于各种医疗保健应用对 3D 细胞培养的需求不断增加,这种增长归因于研究机构和临床实验室以及多家公司之间的合作增加。 例如,Procter &Gamble (P&G) 和英国杜伦大学正在合作创建 3D 皮肤替代品,使用模拟组织的 2D 平台来研究体外衰老过程。 此外,许多学术机构将研发活动的重点放在 3D 培养模型上,以开发治疗各种疾病的新方法。 学术机构和大学研究活动的激增预计将在分析期间推动该领域的增长。
在预测期内,北美将继续占据主导地位,因为有几家製药和生物技术公司与研究机构和临床实验室合作使用 3D 培养技术进行再生医学和药物发现开发。预计将保持这一趋势。 此外,器官移植需求的增加以及专注于技术先进解决方案的研发活动的增加预计将推动该地区采用 3D 细胞培养。 此外,癌症发病率的激增导致政府增加了对癌症□□领域研发的资金和补贴,这可能对 3D 细胞培养市场的增长产生积极影响。 此外,生物技术和製药公司的战略扩张推出了先进的产品,预计将在未来几年推动市场增长。
对利益相关者的主要好处
本报告定量分析了 2021 年至 2031 年 3D 细胞培养市场分析的细分市场、当前趋势、估计和动态,以确定 3D 细胞培养市场的主要机会。
市场研究提供了有关关键驱动因素、市场限制和机会的信息。
波特的五力分析强调了买家和供应商在帮助利益相关者做出以利润为导向的商业决策和加强供应商-买家网络方面的潜力。
对 3D 细胞培养市场细分的详细分析有助于确定总体市场机会。
每个地区的主要国家根据其对全球市场的收入贡献进行映射。
市场参与者定位有助于进行基准测试,并提供对市场参与者当前位置的清晰了解。
本报告分析了区域和全球 3D 细胞培养市场趋势、主要参与者、细分市场、应用领域和市场增长战略。
A 3D cell culture is an in-vitro technique wherein the cells can grow in an artificially created environment. These environments closely resemble the architecture and functioning of the native tissue. 3D cell culture technique helps stimulate cell differentiation, proliferation, and migration by interacting with their three-dimensional surroundings as they would in the in-vivo environment. As 3D cell cultures can mimic the structure, activity, and microenvironment of the in-vivo tissues, this technique has varied applications in the fields of drug screening, regenerative medicine, stem cell therapies, cancer research and cell biology. The extracellular matrix in 3D cell cultures enables cell-cell communication by direct contact as in in-vivo environment by secreting cytokines and trophic factors. These factors are changed in a 2D environment that can significantly affect the cell-cell communication, which in turn can alter the cell morphology and proliferation. As 2D cultures cannot recapitulate the architecture and complex cellular matrices as in 3D cultures, this technique is gaining popularity in healthcare research sector. In addition, 3D cell cultures can provide results with improved efficiency and reduce the cost of overall R&D process.
Based on product, the 3D cell culture market can be categorized into scaffold-based platforms, scaffold-free platforms, gels, bioreactors, microchips, and services. Scaffold-based platforms are used to alter the cell culture procedure by providing a surface on which the cells can easily impart 3D growth. Scaffolds are used in drug discovery and cell expansion, owing to the availability of a variety of materials and structural choices. In addition, there are other advantages related to the use of scaffold-based platforms such as ease of imaging and simple assay protocol. Moreover, the mechanical and biochemical properties of the scaffold can easily be modified as per the need of the application. Thus, this segment is expected to dominate the product segment throughout the forecast period as there is a high demand for scaffold-based platforms for creating 3D cell cultures. Nevertheless, scaffold-based platforms can adsorb test compounds, limit downstream endpoints for analysis, and introduce different biological substances, thereby obstructing the segment growth.
Based on application, the 3D cell culture market is segmented into cancer research, stem cell research, drug discovery, and regenerative medicine. Cancer research segment is anticipated to be the largest growing segment over the analysis period. This is majorly attributed to the advantages offered by 3D cell culture in cancer research, these include ease of altering cell proliferation and morphology, revealing realistic drug response, capturing phenotypic heterogeneity, allowing experimental manipulation in gene expression & cell behavior and representing the tumor microenvironment. Preclinical studies that utilize the benefits of 3D cell culture early on can critically improvise the understanding of cancer biology. These include elimination of poor drug candidates and identification of physiologically relevant targets that were previously inaccessible in 2D cultures. This can largely contribute toward the segment growth.
Based on end user, the global 3D cell culture market is segmented into biotechnology & pharmaceutical companies, contract research laboratories, and academic institutes. The academic institutes segment held a dominant position in the end user segment throughout the analysis period. This growth is due to rise in collaborations between several companies with research institutes and clinical laboratories owing to the rise in demand of 3D cell cultures for various healthcare applications. For instance, Procter & Gamble (P&G) and Durham University based in the UK have collaborated for engineering 3D skin substitutes with the help of tissue-mimetic 2D platforms for studying the process of ageing in-vitro. In addition, many academic institutes have focused their R&D activities toward 3D culture models for developing novel approaches for treating different medical conditions. This surge in research activities across academic institutes and universities is predicted to propel the growth of the segment over the analysis period.
North America is expected to maintain its dominance during the forecast period due to the presence of several pharmaceutical and biotechnology companies that use 3D culture technology in collaboration with research institutes and clinical laboratories for developing regenerative medicines and drug discovery & development. Furthermore, rise in demand for organ transplantation and upsurge in R&D activities focused on technologically advanced solutions is predicted to fuel the adoption of 3D cell culture practices in the region. In addition, surge in incidences of cancer has led the government to increase the funding and grants for R&D in the field of cancer, which may have a positive impact on the 3D cell culture market growth. Moreover, the strategic expansion of biotechnological and pharmaceutical companies has led to launch of advanced products, which are expected to augment the market growth in coming years.
Key Benefits For Stakeholders
This report provides a quantitative analysis of the market segments, current trends, estimations, and dynamics of the 3d cell culture market analysis from 2021 to 2031 to identify the prevailing 3d cell culture market opportunities.
The market research is offered along with information related to key drivers, restraints, and opportunities.
Porter's five forces analysis highlights the potency of buyers and suppliers to enable stakeholders make profit-oriented business decisions and strengthen their supplier-buyer network.
In-depth analysis of the 3d cell culture market segmentation assists to determine the prevailing market opportunities.
Major countries in each region are mapped according to their revenue contribution to the global market.
Market player positioning facilitates benchmarking and provides a clear understanding of the present position of the market players.
The report includes the analysis of the regional as well as global 3d cell culture market trends, key players, market segments, application areas, and market growth strategies.
By Product
By Application
By End User
By Region