精准发酵的技术成长机会

日益激烈的竞争促进了不同行业高影响力、永续的新原材料的出现

传统发酵长期以来一直被使用，特别是在食品生产中。发酵的应用正在扩展到替代蛋白质和其他成分的生产。传统发酵利用自然状态下的微生物生产工业化学品、生物材料、药品、食品和饮料和饮料以及个人护理产品的生物基成分。或者，在生物质发酵中，培养富含蛋白质的微生物，快速生长的微生物生物质成为替代蛋白质原料。儘管传统发酵比化学合成更永续、更环保，但这种製程只能生产有限种类的成分。其他缺点包括需要大量原材料、产量和纯度低、上游加工昂贵且耗时、品质不稳定造成的健康风险以及有毒废弃物和副产品对环境的负面影响。

精准发酵是製造业的新浪潮，它使用优化或基因工程菌株在精确控制的发酵过程中生产成分。各行业的领先公司正在采用精密发酵，以满足对环保化学品和原材料、具有产品增强特性的新原材料、安全供应链和提高生产力日益增长的需求。本报告的范围仅限于精密发酵技术在化学品和材料、食品和饮料、製药和个人护理行业中的应用，这些是对精密发酵影响最大的应用。

合作和策略伙伴关係正在促进该行业的显着成长。美国和欧洲在精准发酵的创新和采用方面处于领先地位。主要产业参与者正致力于扩大精确发酵原料的生产规模并降低生产成本。值得注意的是，合成生物学新兴企业透过原料设计日益影响精准发酵的进步，使该领域成为生物技术公司充满希望的成长机会。这就是我正在做的事情。人工智慧、机器人和合成生物学技术的进步正在带来成长机会。

精密发酵可能永远无法完全取代传统成分，尤其是在食品和饮料和个人护理行业。然而，随着各行业对永续原料的需求不断增加，它们很可能在不久的将来成为主流生产技术，促进各大公司的成长。

本次调查回答的问题

• 精准发酵的产业需求有哪些？什么是精准发酵及其好处？精密发酵有哪些种类和用途？
• 开发精准发酵技术和实现该技术的技术的主要企业有哪些？
• 精密发酵产业的生长促进因子和成长抑制因素有哪些？
• 精准发酵的产业需求和影响有哪些？区域趋势是什么？参与企业有哪些？您将使用什么技术以及该解决方案的用途是什么？使用精密发酵的主要公司有哪些？为什么？您最近有哪些合作伙伴关係和协作活动？精准发酵对应用领域的各种原料有何影响？
• 该行业的资金筹措和智慧财产权 (IP) 活动的趋势是什么？
• 精准发酵产业的成长机会有哪些？
• 精准发酵将如何影响各种应用？克服产业关键障碍的建议策略是什么？分析师对精准发酵的未来有何看法？

目录

战略问题

• 为什么成长如此困难？
• The Strategic Imperative 8（TM）
• 精准发酵产业三大策略挑战的影响
• 成长机会推动Growth Pipeline Engine（TM）
• 调查方法

成长机会分析

• 传统发酵的挑战
• 精密发酵 - 概述
• 精准发酵的分类
• 精准发酵技术类型及比较分析
• 高通量筛选发酵
• 连续发酵
• 连续分批发酵
• pH控制发酵
• 搅拌槽发酵
• 微生物生物反应器发酵
• 主要开发精密发酵技术的公司
• 实现精准发酵的企业
• 精准发酵在终端用途产业的应用－细分
• 生长促进因子
• 成长抑制因素
• 分析范围

应用分析：化学品和材料

• 化学品和材料的精密发酵 - 概述
• 区域/监管趋势
• 化学品和材料的发酵—创新生态系统
• 主要使用精密发酵的企业
• 最近的合作伙伴关係和合作，使化学品和材料生产商业化
• 精准发酵对化学品和原料的影响

应用分析：食品和饮料

• 食品和饮料精密发酵 - 概述
• 区域/监管趋势
• 食品和饮料配料的发酵 - 创新生态系统
• 主要使用精密发酵的企业
• 食品和饮料配料生产商业化的最佳伙伴关係和协作
• 精密发酵对食品和饮料成分的影响

应用分析：製药

• 医药原料精密发酵－概述
• 区域/监管趋势
• 医药原料发酵－创新生态系统
• 发酵药物成分的临床前/临床研究
• 主要使用精密发酵的企业
• 最近在药物成分生产商业化方面的合作伙伴关係和合作
• 精密发酵对药物成分的影响

应用分析：个人护理

• 个人护理产品的精密发酵 - 概述
• 区域/监管趋势
• 个人护理成分发酵 - 创新生态系统
• 发酵个人护理成分的临床前/临床研究
• 主要使用精密发酵的企业
• 最近的合作伙伴关係和合作将个人护理成分生产商业化
• 精密发酵对个人护理成分的影响

资金筹措分析

• 精准发酵申请资金筹措（2020-2023）
• 精准发酵资金筹措专案趋势（2020-2023）
• 精准发酵产业最大受益者（2020-2023）
• 精准发酵产业的重大资金筹措交易

专利分析

• 精准发酵产业智慧财产权活动
• 精密发酵产业知识产权活动（按辖区）
• 精准发酵领域的智慧财产权活动－化学品与材料
• 精密发酵领域的智慧财产权活动 - 化学品和材料（按管辖区）
• 精密发酵领域的智慧财产权活动—食品和饮料
• 精密发酵领域的智慧财产权活动－食品和饮料（依管辖区）
• 精准发酵中的智慧财产权活动-製药
• 精密发酵领域的智慧财产权活动－製药（依管辖区）
• 精密发酵中的知识产权活动 - 个人护理
• 精密发酵中的知识产权活动 - 个人护理（按管辖区）

成长机会领域

• 成长机会一：人工智慧与机器人技术在精准发酵领域的融合
• 成长机会2：新的合成生物学技术
• 成长机会3：素食人口的成长

分析师的观点

• 精密发酵 - 应用影响分析
• 精准发酵的挑战与克服策略
• 精准发酵的未来

附录

下一步

Competitive Intensity Enabling Emergence of New High-impact Sustainable Ingredients for Diverse Industries

Conventional fermentation has long been in use, especially for food production. Fermentation applications have expanded to the production of alternate proteins and other ingredients. Traditional fermentation employs microorganisms in their natural state to produce bio-based ingredients for industrial chemicals, biomaterials, pharmaceuticals, food and beverages, and personal care products. Alternatively, biomass fermentation involves culturing protein-dense microorganisms where the rapidly grown microbial biomass becomes the alternative protein ingredient. While conventional fermentation is more sustainable and environmentally friendly than chemical synthesis, the process can only produce a limited diversity of ingredients. Other drawbacks include the large volumes of feedstock needed, low yield and purity, expensive and time-consuming upstream treatments, health risks due to inconsistent quality, and adverse environmental impact from the toxic waste and byproducts.

Precision fermentation, the production of ingredients using optimized or genetically engineered strains in a precisely controlled fermentation process, is the new wave in manufacturing. To meet the growing needs for environmentally friendly chemicals and ingredients, novel ingredients with product-enhancing properties, securing the supply chain, and higher productivity, major players in diverse industries are adopting precision fermentation. The scope of this report only covers precision fermentation technologies in the chemicals and materials, food and beverage, pharmaceutical, and personal care industries, the applications with the greatest impact on precision fermentation.

Collaborations and strategic partnerships are enabling substantial growth in this industry. The United States and Europe are leading precision fermentation innovation and adoption. Major industry players focus on scaling up the production of precision fermentation-derived ingredients and reducing the cost of production. Notably, synthetic biology start-ups are increasingly influencing advances in precision fermentation by enabling the designing of ingredients, making the field a promising growth opportunity for biotechnology companies. Advancements in AI, robotics, and synthetic biology technologies are enabling growth opportunities.

Precision fermentation may not entirely replace conventional ingredients, especially in the food and beverage and personal care industries; however, with increased demand for sustainable ingredients in various industries, it will soon become a mainstream production technology, enabling growth among major players.

Questions This Research Answers:

• What are the industry needs for precision fermentation? What is precision fermentation and its advantages? What are the different types and applications of precision fermentation?

• Who are the major players developing precision fermentation technologies and enabling technologies?

• What are the drivers and restraints for the growth of the precision fermentation industry?

• What are the industry needs and the impact of precision fermentation? What are the regional trends? Who are the participants in the different application segments? What technologies do they employ, and what are the applications of their solutions? Who are the main adopters, and why are they adopting precision fermentation? What are the recent partnership and collaboration activities? What is the impact of precision fermentation on various ingredients in application segments?

• What are the funding and intellectual property (IP) activity trends in the industry?

• What are the growth opportunities for the precision fermentation industry?

• What is the analyst's perspective on the impact of precision fermentation on different applications, recommended strategies to overcome major hurdles in the industry, and the future of precision fermentation?

Table of Contents

Strategic Imperatives

• Why Is It Increasingly Difficult to Grow?The Strategic Imperative 8™: Factors Creating Pressure on Growth
• The Strategic Imperative 8™
• The Impact of the Top 3 Strategic Imperatives on the Precision Fermentation Industry
• Growth Opportunities Fuel the Growth Pipeline Engine™
• Research Methodology

Growth Opportunity Analysis

• Challenges in Conventional Fermentation
• Precision Fermentation-An Overview
• Precision Fermentation Classification
• Types of Precision Fermentation Techniques and Comparative Analysis
• High-throughput Screening Fermentation
• Continuous Fermentation
• Fed-batch Fermentation
• Controlled-pH Fermentation
• Stirred-tank Fermentation
• Microbial Bioreactor Fermentation
• Key Players Developing Precision Fermentation Technologies
• Precision Fermentation Enabling Players
• Applications of Precision Fermentation in End-user Industries-Segmentation
• Growth Drivers
• Growth Restraints
• Scope of Analysis

Application Analysis: Chemicals and Materials

• Precision Fermentation for Chemicals and Materials-Overview
• Regional and Regulatory Trends
• Chemicals and Materials Fermentation-Innovation Ecosystem
• Key Adopters of Precision Fermentation
• Recent Partnerships and Collaborations for Commercializing Chemical and Material Production
• Impact of Precision Fermentation on Chemical and Material Ingredients

Application Analysis: Food and Beverage

• Precision Fermentation for Food and Beverages-Overview
• Regional and Regulatory Trends
• Food and Beverage Ingredient Fermentation-Innovation Ecosystem
• Key Adopters of Precision Fermentation
• Recent Partnerships and Collaborations for Commercializing Food and Beverage Ingredient Production
• Impact of Precision Fermentation on Food and Beverage Ingredients

Application Analysis: Pharmaceuticals

• Precision Fermentation for Pharmaceutical Ingredients-Overview
• Regional and Regulatory Trends
• Pharmaceutical Ingredient Fermentation-Innovation Ecosystem
• Preclinical/Clinical Studies on Fermented Pharmaceutical Ingredients
• Key Adopters of Precision Fermentation
• Recent Partnerships and Collaborations for Commercializing Pharmaceutical Ingredient Production
• Impact of Precision Fermentation on Pharmaceutical Ingredients

Application Analysis: Personal Care

• Precision Fermentation for Personal Care Products-Overview
• Regional and Regulatory Trends
• Personal Care Ingredient Fermentation-Innovation Ecosystem
• Preclinical/Clinical Studies on Fermented Personal Care Ingredients
• Key Adopters of Precision Fermentation
• Recent Partnerships and Collaborations for Commercializing Personal Care Ingredient Production
• Impact of Precision Fermentation on Personal Care Ingredients

Funding Analysis

• Funding across Applications of Precision Fermentation, 2020-2023
• Funding Deal Trends for Precision Fermentation, 2020-2023
• Top Beneficiaries of the Precision Fermentation Industry, 2020-2023
• Notable Funding Deals in the Precision Fermentation Industry

Patent Analysis

• IP Activity in Precision Fermentation Industry
• IP Activity in the Precision Fermentation Industry, by Jurisdiction
• IP Activity in Precision Fermentation-Chemicals and Materials
• IP Activity in Precision Fermentation-Chemicals and Materials, by Jurisdiction
• IP Activity in Precision Fermentation-Food and Beverage
• IP Activity in Precision Fermentation-Food and Beverage, by Jurisdiction
• IP Activity in Precision Fermentation-Pharmaceuticals
• IP Activity in Precision Fermentation-Pharmaceuticals, by Jurisdiction
• IP Activity in Precision Fermentation-Personal Care
• IP Activity in Precision Fermentation-Personal Care Ingredients, by Jurisdiction

Growth Opportunity Universe

• Growth Opportunity 1: Integration of AI and Robotics in Precision Fermentation
• Growth Opportunity 2: Emerging Synthetic Biology Technologies
• Growth Opportunity 3: Growing Vegan Population

Analyst's Perspective

• Precision Fermentation-Application Impact Analysis
• Challenges of Precision Fermentation and Strategies to Overcome
• The Future of Precision Fermentation

Appendix

• Technology Readiness Levels (TRL): Explanation
• Heat Map Analysis Factors-Definitions

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